PSIP1 Monoclonal antibody, PBS Only (Capture) 67723-1-PBS proteintech
$699.00
In stock
SKU
67723-1-PBS
| Catalog Number | 67723-1-PBS |
| Synonyms | 1E9E7, CLL associated antigen KW 7, CLL-associated antigen KW-7, DFS70, LEDGF |
| Host | Mouse |
| Reactivity | human, mouse |
| Form | Liquid |
| Formulation | PBS Only |
| Applications | WB, IF/ICC, Cytometric bead array, Sandwich ELISA, Indirect ELISA |
| Host / Isotype | Mouse / IgG1 |
| Tested Reactivity | human, mouse |
| Class | Monoclonal |
| Type | Antibody |
| Immunogen | CatNo: Ag30562 Product name: Recombinant human PSIP1 protein Source: e coli. -derived, PET28a Tag: 6*His Domain: 104-325 aa of NM_021144 Sequence: ASSDVEVEEKETSVSKEDTDHEEKASNEDVTKAVDITTPKAARRGRKRKAEKQVETEEAGVVTTATASVNLKVSPKRGRPAATEVKIPKPRGRPKMVKQPCPSESDIITEEDKSKKKGQEEKQPKKQPKKDEEGQKEEDKPRKEPDKKEGKKEVESKRKNLAKTGVTSTSDSEEEGDDQEGEKKRKGGRNFQTAHRRNMLKGQHEKEAADRKRKQEEQMETE Predict reactive species |
| Full Name | PC4 and SFRS1 interacting protein 1 |
| Calculated Molecular Weight | 60 kDa |
| Observed Molecular Weight | 75 kDa |
| GenBank Accession Number | NM_021144 |
| Gene Symbol | PSIP1 |
| Gene ID (NCBI) | 11168 |
| RRID | AB_3670379 |
| Conjugate | Unconjugated |
| Purification Method | Protein G purification |
| UNIPROT ID | O75475 |
| Storage Buffer | PBS only, pH 7.3. |
| Storage Conditions | Store at -80°C. |
| Citations | - |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Clone Number | 1E9E7 |
| Conjugation | Unconjugated |
PSIP1, also known as PC4 and SRSF1 Interacting Protein 1 or Lens Epithelium-Derived Growth Factor (LEDGF), is a transcriptional coactivator involved in neuroepithelial stem cell differentiation and neurogenesis. It also plays a role in lens epithelial cell gene regulation and stress responses. It is a chromatin-associated protein with histone chaperone activity, involved in transcriptional elongation. PSIP1 may act as an adapter to coordinate pre-mRNA splicing. PSIP1 encodes two protein isoforms with molecular masses of 52 and 75 kDa. p52 and p75 were identified as interacting with transcription factor PC4 and shown to act as transcriptional coactivators.
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