PTPN14 Polyclonal antibody 18053-1-AP proteintech
$149.00
In stock
SKU
18053-1-AP
| Catalog Number | 18053-1-AP |
| Synonyms | PEZ, PTP36, PTPN14 |
| Host | Rabbit |
| Reactivity | human and More (1) |
| Reactivity | human, canine |
| Form | Liquid |
| Formulation | PBS, Azide, Glycerol |
| Applications | WB, IHC, ELISA |
| Host / Isotype | Rabbit / IgG |
| Tested Applications — Positive WB detected in | HeLa cells, K-562 cells |
| Tested Applications — Positive IHC detected in | human placenta tissue, human brain tissue, human kidney tissue, human lung tissue, human ovary tissue, human skin tissue, human spleen tissue Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0 |
| Recommended Dilutions — Western Blot (WB) | WB : 1:500-1:2000 |
| Recommended Dilutions — Immunohistochemistry (IHC) | IHC : 1:20-1:200 |
| Positive WB detected in | HeLa cells, K-562 cells |
| Positive IHC detected in | human placenta tissue, human brain tissue, human kidney tissue, human lung tissue, human ovary tissue, human skin tissue, human spleen tissue Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0 |
| Western Blot (WB) | WB : 1:500-1:2000 |
| Immunohistochemistry (IHC) | IHC : 1:20-1:200 |
| Tested Reactivity | human |
| Cited Reactivity | human, canine |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | CatNo: Ag12571 Product name: Recombinant human PTPN14 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 1-351 aa of BC101754 Sequence: MPFGLKLRRTRRYNVLSKNCFVTRIRLLDSNVIECTLSVESTGQECLEAVAQRLELRETHYFGLWFLSKSQQARWVELEKPLKKHLDKFANEPLLFFGVMFYVPNVSWLQQEATRYQYYLQVKKDVLEGRLRCTLDQVIRLAGLAVQADFGDYNQFDSQDFLREYVLFPMDLALEEAVLEELTQKVAQEHKAHSGILPAEAELMYINEVERLDGFGQEIFPVKDNHGNCVHLGIFFMGIFVRNRIGRQAVIYRWNDMGNITHNKSTILVELINKEETALFHTDDIENAKYISRLFATRHKFYKQNKICTEQSNSPPPIRRQPTWSRSSLPRQQPYILPPVHVQCGEHYSET Predict reactive species |
| Full Name | protein tyrosine phosphatase, non-receptor type 14 |
| Calculated Molecular Weight | 1187 aa, 135 kDa |
| Observed Molecular Weight | 150 kDa |
| GenBank Accession Number | BC101754 |
| Gene Symbol | PTPN14 |
| Gene ID (NCBI) | 5784 |
| RRID | AB_2284584 |
| Conjugate | Unconjugated |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | Q15678 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA. |
| IHC protocol for PTPN14 antibody 18053-1-AP | Download protocol |
| WB protocol for PTPN14 antibody 18053-1-AP | Download protocol |
| human | WB,IHC IUBMB Life Oncogenic Role of PTPN14 in Pancreatic Cancer Through β-Catenin/NF-κB Pathway Activation. Authors - Danni Luo KD Validated View Article |
| canine | WB Biologicals CDC20 is a potential target gene to inhibit the tumorigenesis of MDCK cells Authors - Zhenbin Liu View Article |
| Citations | 2 |
| Dilutions | WB : 1:500-1:2000 IHC : 1:20-1:200 |
| Isotype | IgG |
| Clonality | Polyclonal |
| Clone Number | - |
| Conjugation | Unconjugated |
PTPN14 (tyrosine-protein phosphatase non-receptor type 14) is also named as PEZ and belongs to the protein-tyrosine phosphatase family and non-receptor class subfamily. It is a multi-domain protein expressed in breast, kidney, skeletal muscle, lung, placenta, and characterized by an N-terminal FERM domain and a C-terminal PTP domain with an intervening sequence containing an acidic region and a putative SH3 domain-binding sequence (PMID: 21701840). Defects in PTPN14 are a cause of choanal atresia and lymphedema (CHATLY). Protocols Product Specific Protocols IHC protocol for PTPN14 antibody 18053-1-AP Download protocol WB protocol for PTPN14 antibody 18053-1-AP Download protocol Standard Protocols Click here to view our Standard Protocols
Publications
- Oncogenic Role of PTPN14 in Pancreatic Cancer Through β-Catenin/NF-κB Pathway Activation.
Journal: IUBMB Life | Authors: Danni Luo KD Validated | Species: human | Application: WB,IHC - CDC20 is a potential target gene to inhibit the tumorigenesis of MDCK cells
Journal: Biologicals | Authors: Zhenbin Liu | Species: canine | Application: WB
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