Pregnancy Zone Protein Polyclonal antibody 21742-1-AP proteintech
$149.00
In stock
SKU
21742-1-AP
| Catalog Number | 21742-1-AP |
| Synonyms | PZP, pregnancy-zone protein |
| Host | Rabbit |
| Reactivity | human |
| Form | Liquid |
| Formulation | PBS, Azide, Glycerol |
| Applications | WB, IHC, IF, ELISA |
| Applications | WB, IHC, ELISA |
| Host / Isotype | Rabbit / IgG |
| Tested Applications — Positive WB detected in | human plasma, human placenta tissue |
| Tested Applications — Positive IHC detected in | human placenta tissue, human brain tissue Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0 |
| Recommended Dilutions — Western Blot (WB) | WB : 1:5000-1:20000 |
| Recommended Dilutions — Immunohistochemistry (IHC) | IHC : 1:50-1:500 |
| Positive WB detected in | human plasma, human placenta tissue |
| Positive IHC detected in | human placenta tissue, human brain tissue Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0 |
| Western Blot (WB) | WB : 1:5000-1:20000 |
| Immunohistochemistry (IHC) | IHC : 1:50-1:500 |
| Tested Reactivity | human |
| Cited Reactivity | human |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | CatNo: Ag16471 Product name: Recombinant human PZP protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 341-690 aa of BC111756 Sequence: ITAHYTLNRQAMGELSELSFHYLIMAKGVIVRSGTHTLPVESGDMKGSFALSFPVESDVAPIARMFIFAILPDGEVVGDSEKFEIENCLANKVDLSFSPAQSPPASHAHLQVAAAPQSLCALRAVDQSVLLMKPEAELSVSSVYNLLTVKDLTNFPDNVDQQEEEQGHCPRPFFIHNGAIYVPLSSNEADIYSFLKGMGLKVFTNSKIRKPKSCSVIPSVSAGAVGQGYYGAGLGVVERPYVPQLGTYNVIPLNNEQSSGPVPETVRSYFPETWIWELVAVNSSGVAEVGVTVPDTITEWKAGAFCLSEDAGLGISSTASLRAFQPFFVELTMPYSVIRGEVFTLKATVL Predict reactive species |
| Full Name | pregnancy-zone protein |
| Calculated Molecular Weight | 1482 aa, 164 kDa |
| Observed Molecular Weight | 180 kDa |
| GenBank Accession Number | BC111756 |
| Gene Symbol | Pregnancy Zone Protein |
| Gene ID (NCBI) | 5858 |
| RRID | AB_10732823 |
| Conjugate | Unconjugated |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | P20742 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA. |
| IHC protocol for Pregnancy Zone Protein antibody 21742-1-AP | Download protocol |
| WB protocol for Pregnancy Zone Protein antibody 21742-1-AP | Download protocol |
| human | WB J Gene Med Integrated Single-Cell Transcriptome and eQTL Analyses Reveal the Role of PZP in Aging and Chronic Kidney Disease Authors - Xinhui Huang View Article |
| Citations | 3 |
| Dilutions | WB : 1:5000-1:20000 IHC : 1:50-1:500 |
| Isotype | IgG |
| Clonality | Polyclonal |
| Clone Number | - |
| Conjugation | Unconjugated |
Pregnancy Zone Protein (PZP) is an immunosuppressive protein that is expressed by the placenta. The PZP is a thiol ester-containing alpha macroglobulin protein that controls the proteolytic pathways during pregnancy and contributes to maintaining the immunologically privileged status of the fetus. Recently PZP over-expression has been described as a novel biomarker for predicting the prognosis of hepatocellular carcinoma and its high expression has been reported in solid tumors. Protocols Product Specific Protocols IHC protocol for Pregnancy Zone Protein antibody 21742-1-AP Download protocol WB protocol for Pregnancy Zone Protein antibody 21742-1-AP Download protocol Standard Protocols Click here to view our Standard Protocols
Publications
- iTRAQ plasma proteomics analysis for candidate biomarkers of type 2 incipient diabetic nephropathy.
Journal: Clin Proteomics | Authors: Hongmei Lu | Species: human | Application: WB - Integrated Single-Cell Transcriptome and eQTL Analyses Reveal the Role of PZP in Aging and Chronic Kidney Disease
Journal: J Gene Med | Authors: Xinhui Huang | Species: human | Application: WB - Mesenchymal stromal cells-derived small extracellular vesicles protect against UV-induced photoaging via regulating pregnancy zone protein
Journal: Stem Cells Transl Med | Authors: Zixuan Sun | Application: WB,IHC,IF
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