Phospho-CD19 (Tyr531) Recombinant monoclonal antibody 87153-1-RR proteintech
$149.00
In stock
SKU
87153-1-RR
| Catalog Number | 87153-1-RR |
| Synonyms | CD19 (Tyr531), p-CD19, p-CD19 (Tyr531), p-CD19(Tyr531), Phospho CD19 |
| Host | Rabbit |
| Reactivity | human |
| Form | Liquid |
| Formulation | PBS, Azide, Glycerol |
| Applications | WB, ELISA |
| Host / Isotype | Rabbit / IgG |
| Tested Applications — Positive WB detected in | Ramos cells |
| Recommended Dilutions — Western Blot (WB) | WB : 1:5000-1:50000 |
| Positive WB detected in | Ramos cells |
| Western Blot (WB) | WB : 1:5000-1:50000 |
| Tested Reactivity | human |
| Class | Recombinant |
| Type | Antibody |
| Immunogen | Peptide Predict reactive species |
| Full Name | CD19 molecule |
| Calculated Molecular Weight | 556 aa, 61 kDa |
| Observed Molecular Weight | 95 kDa |
| GenBank Accession Number | NM_001770 |
| Gene Symbol | CD19 |
| Gene ID (NCBI) | 930 |
| ENSEMBL Gene ID | ENSG00000177455 |
| RRID | AB_3745374 |
| Conjugate | Unconjugated |
| Purification Method | Protein A purification |
| UNIPROT ID | P15391 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA. |
| WB protocol for Phospho-CD19 (Tyr531) antibody 87153-1-RR | Download protocol |
| Citations | - |
| Dilutions | WB : 1:5000-1:50000 |
| Isotype | IgG |
| Clonality | Recombinant |
| Clone Number | 252332G9 |
| Conjugation | Unconjugated |
CD19 is a 95 kDa type I transmembrane glycoprotein belonging to the immunoglobulin superfamily. Phospho-CD19 (Tyr531) is a phosphorylated form of CD19, which is a protein involved in B cell receptor (BCR) signaling and plays a crucial role in B cell development and function. Phosphorylation of CD19 at Tyr531 is known to recruit PI3K activity leading to Akt activation and attendant S473 phosphorylation. This activation of BCR induces multiple oncogenic signals and treatment with ibrutinib prevents preferentially the activation of BTK in both patients with ABC-like and GCB-like molecular features. (PMID: 20038598) Protocols Product Specific Protocols WB protocol for Phospho-CD19 (Tyr531) antibody 87153-1-RR Download protocol Standard Protocols Click here to view our Standard Protocols
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