Phospho-HSP27 (Ser78) Polyclonal antibody 28900-1-AP proteintech
$149.00
In stock
SKU
28900-1-AP
| Catalog Number | 28900-1-AP |
| Synonyms | DMPK binding protein, heat shock 27kDa protein 2, Heat shock protein beta 2, Hs.78846, Hsp B1, HSP27, Phospho-HSP27 (Ser78) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat and More (1) |
| Reactivity | human, mouse, rat |
| Form | Liquid |
| Formulation | PBS, Azide, Glycerol |
| Applications | WB, ELISA |
| Host / Isotype | Rabbit / IgG |
| Tested Applications — Positive WB detected in | TNF-alpha treated HeLa cells, Calyculin A treated HeLa cells, Calyculin A treated PC-3 cells |
| Recommended Dilutions — Western Blot (WB) | WB : 1:500-1:2000 |
| Positive WB detected in | TNF-alpha treated HeLa cells, Calyculin A treated HeLa cells, Calyculin A treated PC-3 cells |
| Western Blot (WB) | WB : 1:500-1:2000 |
| Tested Reactivity | Human, Mouse, Rat |
| Cited Reactivity | human |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide Predict reactive species |
| Full Name | heat shock 27kDa protein 1 |
| Calculated Molecular Weight | 19-23 kDa |
| Observed Molecular Weight | 27-30 kDa |
| GenBank Accession Number | BC012768 |
| Gene Symbol | HSPB1 |
| Gene ID (NCBI) | 3315 |
| RRID | AB_2881230 |
| Conjugate | Unconjugated |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | P04792 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA. |
| WB protocol for Phospho-HSP27 (Ser78) antibody 28900-1-AP | Download protocol |
| human | WB JOR Spine Phosphorylated heat shock protein 27 improves the bone formation ability of osteoblasts and bone marrow stem cells from patients with adolescent idiopathic scoliosis Authors - Sihan He View Article |
| Citations | 2 |
| Dilutions | WB : 1:500-1:2000 |
| Isotype | IgG |
| Clonality | Polyclonal |
| Clone Number | - |
| Conjugation | Unconjugated |
HSPB1, also named as HSP27, belongs to the mammalian small HSP family widely expressed in cells including the cytoplasm and nucleus. It has been reported that HSPB1 plays a key role in stress resistance, actin organization and numerous biological processes. HSPB1 can be phosphorylated in different stimulation such as cytokines, growth factors and peptide hormones on the site of Ser15, Ser78 and Ser82 by MAPKAP2 kinase. The phosphorylation of HSPB1 leads to a decrease in the size of HSPB1 oligomers. HSPB1 is associated with amyotrophic lateral sclerosis (ALS) (PMID: 8542580, 11960785, 10383393, 32231288) Protocols Product Specific Protocols WB protocol for Phospho-HSP27 (Ser78) antibody 28900-1-AP Download protocol Standard Protocols Click here to view our Standard Protocols
Publications
- PARP1 stabilizes FOXN3 to suppress pulmonary fibrosis through p38-related feedback regulation.
Journal: Sci Adv | Authors: Xinxing Zhu | Species: human | Application: WB - Phosphorylated heat shock protein 27 improves the bone formation ability of osteoblasts and bone marrow stem cells from patients with adolescent idiopathic scoliosis
Journal: JOR Spine | Authors: Sihan He | Species: human | Application: WB
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