Phospho-LAT (Tyr220) Recombinant monoclonal antibody 87289-1-RR proteintech
$149.00
In stock
SKU
87289-1-RR
| Catalog Number | 87289-1-RR |
| Synonyms | LAT (Tyr220), Phospho LAT (Tyr220), Phospho-LAT, p-LAT (Tyr220), p-LAT (Y220) |
| Host | Rabbit |
| Reactivity | human |
| Form | Liquid |
| Formulation | PBS, Azide, Glycerol |
| Applications | WB, ELISA |
| Host / Isotype | Rabbit / IgG |
| Tested Applications — Positive WB detected in | Jurkat cells |
| Recommended Dilutions — Western Blot (WB) | WB : 1:1000-1:8000 |
| Positive WB detected in | Jurkat cells |
| Western Blot (WB) | WB : 1:1000-1:8000 |
| Tested Reactivity | human |
| Class | Recombinant |
| Type | Antibody |
| Immunogen | Peptide Predict reactive species |
| Full Name | linker for activation of T cells |
| Calculated Molecular Weight | 262 aa, 28 kDa |
| Observed Molecular Weight | 36 kDa, 38 kDa |
| GenBank Accession Number | BC011563 |
| Gene Symbol | LAT |
| Gene ID (NCBI) | 27040 |
| RRID | AB_3745449 |
| Conjugate | Unconjugated |
| Purification Method | Protein A purification |
| UNIPROT ID | O43561 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA. |
| WB protocol for Phospho-LAT (Tyr220) antibody 87289-1-RR | Download protocol |
| Citations | - |
| Dilutions | WB : 1:1000-1:8000 |
| Isotype | IgG |
| Clonality | Recombinant |
| Clone Number | 252580D5 |
| Conjugation | Unconjugated |
LAT is a membrane-localized adaptor protein which is primarily concentrated in microdomains by palmitoylation. Phospho-LAT (Tyr220) is a phosphorylated form of the Linker for Activation of T cells (LAT), a protein that plays a pivotal role in T cell receptor (TCR) signaling. LAT is involved in the assembly of the signaling complex that leads to T cell activation. Upon TCR engagement, LAT becomes phosphorylated at multiple tyrosine residues, including Tyr220. (PMID: 38746248) Protocols Product Specific Protocols WB protocol for Phospho-LAT (Tyr220) antibody 87289-1-RR Download protocol Standard Protocols Click here to view our Standard Protocols
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