Phospho-RPS6KA3 (Ser227) Recombinant monoclonal antibody, PBS Only 87534-1-PBS proteintech
$699.00
In stock
SKU
87534-1-PBS
| Catalog Number | 87534-1-PBS |
| Synonyms | p90RSK3 (phospho Ser227), Phospho RSK2 (Ser227), Phospho-RPS6KA3, Phospho-RSK2, Phospho-RSK2 (Ser227) |
| Host | Rabbit |
| Reactivity | human |
| Form | Liquid |
| Formulation | PBS Only |
| Applications | WB, FC (Intra), Indirect ELISA |
| Host / Isotype | Rabbit / IgG |
| Tested Reactivity | human |
| Class | Recombinant |
| Type | Antibody |
| Immunogen | Peptide Predict reactive species |
| Full Name | ribosomal protein S6 kinase, 90kDa, polypeptide 3 |
| Calculated Molecular Weight | 740 aa, 84 kDa |
| Observed Molecular Weight | 84 kDa |
| GenBank Accession Number | BC096301 |
| Gene Symbol | RSK2 |
| Gene ID (NCBI) | 6197 |
| RRID | AB_3745605 |
| Conjugate | Unconjugated |
| Purification Method | Protein A purification |
| UNIPROT ID | P51812 |
| Storage Buffer | PBS only, pH 7.3. |
| Storage Conditions | Store at -80°C. |
| Citations | - |
| Isotype | IgG |
| Clonality | Recombinant |
| Clone Number | 252865C9 |
| Conjugation | Unconjugated |
Ribosomal S6 Kinase 2 (RSK2), a member of the p90RSK family of serine/threonine kinases, is known to be phosphorylated at Ser227 and Th577 in response to Adriamycin-induced DNA damage. This phosphorylation promotes RSK2 nuclear translocation and enhances RSK2 and Atm interactions in the nuclear fraction, playing an important role in the DNA damage pathway that maintains genomic stability by mediating cell cycle progression and DNA repair.
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