Rat AGER/RAGE Recombinant monoclonal antibody, PBS Only 83759-4-PBS proteintech
$699.00
In stock
SKU
83759-4-PBS
| Catalog Number | 83759-4-PBS |
| Synonyms | RAGE, AGER, Advanced glycosylation end product-specific receptor, 240706F7 |
| Host | Rabbit |
| Reactivity | rat |
| Form | Liquid |
| Formulation | PBS Only |
| Applications | WB, IF-P, ELISA |
| Host / Isotype | Rabbit / IgG |
| Tested Reactivity | rat |
| Class | Recombinant |
| Type | Antibody |
| Immunogen | Fusion Protein Predict reactive species |
| Full Name | advanced glycosylation end product-specific receptor |
| Calculated Molecular Weight | 43 kDa |
| Observed Molecular Weight | 45 kDa, 58 kDa |
| Gene Symbol | Ager |
| Gene ID (NCBI) | 81722 |
| RRID | AB_3671354 |
| Conjugate | Unconjugated |
| Purification Method | Protein A purfication |
| UNIPROT ID | Q63495 |
| Storage Buffer | PBS only, pH 7.3. |
| Storage Conditions | Store at -80°C. |
| Citations | - |
| Isotype | IgG |
| Clonality | Recombinant |
| Clone Number | 240706F7 |
| Conjugation | Unconjugated |
Advanced glycosylation end product-specific receptor (AGER, also known as RAGE) is a member of the immunoglobulin superfamily of cell surface receptors, which interacts with distinct families of ligands, mediating diverse functions in a broad array of cell types including cellular migration, proliferation, survival and apoptosis (PMID: 12645002; 17425919). It senses endogenous stress signals with a broad ligand repertoire including advanced glycation end products, S100 proteins, high-mobility group box 1 protein/HMGB1, amyloid beta/APP oligomers, nucleic acids, phospholipids and glycosaminoglycans (PMID: 19910580; 28627626). It interacts with distinct molecules implicated in homeostasis, development, inflammation, and certain diseases such as diabetes and Alzheimer's disease (PMID: 26253613; 31079281).
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