CoraLite® Plus 488-conjugated RB1CC1 Polyclonal antibody CL488-10069 proteintech
$479.00
In stock
SKU
CL488-10069
| Catalog Number | CL488-10069 |
| Synonyms | CC1, FAK family kinase-interacting protein of 200 kDa, KIAA0203, RB1CC 1, RB1-inducible coiled-coil protein 1 |
| Host | Rabbit |
| Reactivity | human |
| Form | Liquid |
| Formulation | PBS, Proclin300, BSA, Glycerol |
| Applications | IF/ICC, FC (Intra) |
| Host / Isotype | Rabbit / IgG |
| Tested Applications — Positive IF/ICC detected in | HeLa cells |
| Tested Applications — Positive FC (Intra) detected in | HepG2 cells |
| Recommended Dilutions — Immunofluorescence (IF)/ICC | IF/ICC : 1:50-1:500 |
| Recommended Dilutions — Flow Cytometry (FC) (INTRA) | FC (INTRA) : 0.80 ug per 10^6 cells in a 100 µl suspension |
| Positive IF/ICC detected in | HeLa cells |
| Positive FC (Intra) detected in | HepG2 cells |
| Immunofluorescence (IF)/ICC | IF/ICC : 1:50-1:500 |
| Flow Cytometry (FC) (INTRA) | FC (INTRA) : 0.80 ug per 10^6 cells in a 100 µl suspension |
| Tested Reactivity | human |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | CatNo: Ag0003 Product name: Recombinant human RB1CC1 protein Source: e coli. -derived, Unknow Tag: N/A Domain: FIP200 of BC017556 Sequence: Predict reactive species |
| Full Name | RB1-inducible coiled-coil 1 |
| Calculated Molecular Weight | 1594 aa, 183 kDa |
| Observed Molecular Weight | 183 kDa |
| GenBank Accession Number | BC017556 |
| Gene Symbol | RB1CC1 |
| Gene ID (NCBI) | 9821 |
| RRID | AB_3672427 |
| Conjugate | CoraLite® Plus 488 Fluorescent Dye |
| Excitation/Emission Maxima Wavelengths | 493 nm / 522 nm |
| Excitation Laser | Blue laser (488 nm) |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | Q8TDY2 |
| Storage Buffer | PBS with 50% glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3. |
| Storage Conditions | Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. |
| FC protocol for CL Plus 488 RB1CC1 antibody CL488-10069 | Download protocol |
| IF protocol for CL Plus 488 RB1CC1 antibody CL488-10069 | Download protocol |
| Citations | - |
| Dilutions | IF/ICC : 1:50-1:500 FC (INTRA) : 0.80 ug per 10^6 cells in a 100 µl suspension |
| Isotype | IgG |
| Clonality | Polyclonal |
| Clone Number | - |
| Conjugation | CoraLite® Plus 488 |
RB1CC1, also named as RBICC, is implicated in the regulation of RB1 expression and functions as a DNA-binding transcription factor. It is a potent regulator of the RB1 pathway and a mediator that plays a crucial role in muscular differentiation. Its expression is, thus, a prerequisite for myogenic differentiation. Involved in autophagy. RB1CC1 is required for autophagosome formation. It is probably involved in the tumorigenesis of breast cancer. RB1CC1 is frequently mutated in breast cancer and shows characteristics of a classical tumor suppressor gene. This antibody is a rabbit polyclonal antibody raised against residues near the C terminus of human RB1CC1. Protocols Product Specific Protocols FC protocol for CL Plus 488 RB1CC1 antibody CL488-10069 Download protocol IF protocol for CL Plus 488 RB1CC1 antibody CL488-10069 Download protocol Standard Protocols Click here to view our Standard Protocols
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