RNGTT Polyclonal antibody 12430-1-AP proteintech
$149.00
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SKU
12430-1-AP
| Catalog Number | 12430-1-AP |
| Synonyms | CAP1A, GTase, GTP RNA guanylyltransferase, GTP--RNA guanylyltransferase, hCAP |
| Host | Rabbit |
| Reactivity | human, mouse, rat and More (1) |
| Reactivity | human, mouse, rat, pig |
| Form | Liquid |
| Formulation | PBS, Azide, Glycerol |
| Applications | WB, IP, ELISA |
| Host / Isotype | Rabbit / IgG |
| Tested Applications — Positive WB detected in | human kidney tissue |
| Tested Applications — Positive IP detected in | mouse kidney tissue |
| Recommended Dilutions — Western Blot (WB) | WB : 1:500-1:1000 |
| Recommended Dilutions — Immunoprecipitation (IP) | IP : 0.5-4.0 ug for 1.0-3.0 mg of total protein lysate |
| Positive WB detected in | human kidney tissue |
| Positive IP detected in | mouse kidney tissue |
| Western Blot (WB) | WB : 1:500-1:1000 |
| Immunoprecipitation (IP) | IP : 0.5-4.0 ug for 1.0-3.0 mg of total protein lysate |
| Tested Reactivity | human, mouse, rat |
| Cited Reactivity | human, pig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | CatNo: Ag3105 Product name: Recombinant human RNGTT protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 242-598 aa of BC019954 Sequence: TQVTTQPKLGEVQQKCHQFCGWEGSGFPGAQPVSMDKQNIKLLDLKPYKVSWKADGTRYMMLIDGTNEVFMIDRDNSVFHVSNLEFPFRKDLRMHLSNTLLDGEMIIDRVNGQAVPRYLIYDIIKFNSQPVGDCDFNVRLQCIEREIISPRHEKMKTGLIDKTQEPFSVRNKPFFDICTSRKLLEGNFAKEVSHEMDGLIFQPTGKYKPGRCDDILKWKPPSLNSVDFRLKITRMGGEGLLPQNVGLLYVGGYERPFAQIKVTKELKQYDNKIIECKFENNSWVFMRQRTDKSFPNAYNTAMAVCNSISNPVTKEMLFEFIDRCTAASQGQKRKHHLDPDTELMPPPPPKRPHPLT Predict reactive species |
| Full Name | RNA guanylyltransferase and 5'-phosphatase |
| Calculated Molecular Weight | 597 aa, 69 kDa |
| Observed Molecular Weight | 69 kDa |
| GenBank Accession Number | BC019954 |
| Gene Symbol | RNGTT |
| Gene ID (NCBI) | 8732 |
| RRID | AB_2181385 |
| Conjugate | Unconjugated |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | O60942 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA. |
| IP protocol for RNGTT antibody 12430-1-AP | Download protocol |
| WB protocol for RNGTT antibody 12430-1-AP | Download protocol |
| human | WB Mol Cell Redundant pathways for removal of defective RNA polymerase II complexes at a promoter-proximal pause checkpoint Authors - Daniel Blears View Article |
| pig | WB Vet Microbiol Transcriptomic-proteomic integration reveals RNGTT as a critical host factor mediating the replication of virulent but not attenuated SADS-CoV. Authors - Zexin Chen View Article |
| Citations | 2 |
| Dilutions | WB : 1:500-1:1000 IP : 0.5-4.0 ug for IP and 0.5-4.0 ug for 1.0-3.0 mg of total protein lysate for WB |
| Isotype | IgG |
| Clonality | Polyclonal |
| Clone Number | - |
| Conjugation | Unconjugated |
RNGTT(mRNA-capping enzyme) is also named as HCAP1, HCE, CAP1A. In the N-terminal section it belongs to the non-receptor class of the protein-tyrosine phosphatase family and in the C-terminal section it belongs to the eukaryotic GTase family. It is a bifunctional 597-amino acid protein with RNA triphosphatase and RNA guanylyltransferase activities(PMID:9545288). It has 4 isoforms produced by alternative splicing. Protocols Product Specific Protocols IP protocol for RNGTT antibody 12430-1-AP Download protocol WB protocol for RNGTT antibody 12430-1-AP Download protocol Standard Protocols Click here to view our Standard Protocols
Publications
- Redundant pathways for removal of defective RNA polymerase II complexes at a promoter-proximal pause checkpoint
Journal: Mol Cell | Authors: Daniel Blears | Species: human | Application: WB - Transcriptomic-proteomic integration reveals RNGTT as a critical host factor mediating the replication of virulent but not attenuated SADS-CoV.
Journal: Vet Microbiol | Authors: Zexin Chen | Species: pig | Application: WB
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