CoraLite® Plus 488-conjugated RYBP Monoclonal antibody CL488-68130 proteintech
$479.00
In stock
SKU
CL488-68130
| Catalog Number | CL488-68130 |
| Synonyms | 2C6G7, AAP1, APAP 1, APAP-1, Apoptin-associating protein 1 |
| Host | Mouse |
| Reactivity | human, mouse |
| Form | Liquid |
| Formulation | PBS, Proclin300, BSA, Glycerol |
| Applications | FC (Intra) |
| Host / Isotype | Mouse / IgG1 |
| Tested Applications — Positive FC (Intra) detected in | A431 cells |
| Recommended Dilutions — Flow Cytometry (FC) (INTRA) | FC (INTRA) : 0.80 ug per 10^6 cells in a 100 µl suspension |
| Positive FC (Intra) detected in | A431 cells |
| Flow Cytometry (FC) (INTRA) | FC (INTRA) : 0.80 ug per 10^6 cells in a 100 µl suspension |
| Tested Reactivity | human, mouse |
| Class | Monoclonal |
| Type | Antibody |
| Immunogen | CatNo: Ag31715 Product name: Recombinant human RYBP protein Source: e coli. -derived, PET28a Tag: 6*His Domain: 1-228 aa of BC014959 Sequence: MTMGDKKSPTRPKRQAKPAADEGFWDCSVCTFRNSAEAFKCSICDVRKGTSTRKPRINSQLVAQQVAQQYATPPPPKKEKKEKVEKQDKEKPEKDKEISPSVTKKNTNKKTKPKSDILKDPPSEANSIQSANATTKTSETNHTSRPRLKNVDRSTAQQLAVTVGNVTVIITDFKEKTRSSSTSSSTVTSSAGSEQQNQSSSGSESTDKGSSRSSTPKGDMSAVNDESF Predict reactive species |
| Full Name | RING1 and YY1 binding protein |
| Calculated Molecular Weight | 228 aa, 25 kDa |
| Observed Molecular Weight | 32 kDa |
| GenBank Accession Number | BC014959 |
| Gene Symbol | RYBP |
| Gene ID (NCBI) | 23429 |
| RRID | AB_3084411 |
| Conjugate | CoraLite® Plus 488 Fluorescent Dye |
| Excitation/Emission Maxima Wavelengths | 493 nm / 522 nm |
| Excitation Laser | Blue laser (488 nm) |
| Purification Method | Protein G purification |
| UNIPROT ID | Q8N488 |
| Storage Buffer | PBS with 50% glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3. |
| Storage Conditions | Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. |
| FC protocol for CL Plus 488 RYBP antibody CL488-68130 | Download protocol |
| Citations | - |
| Dilutions | FC (INTRA) : 0.80 ug per 10^6 cells in a 100 µl suspension |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Clone Number | 2C6G7 |
| Conjugation | CoraLite® Plus 488 |
Polycomb repressive complexes (PRCs) are important chromatin regulators of embryonic stem (ES) cell function [PMID:22269950]. RYBP binds Polycomb H2A monoubiquitin ligases Ring1A and Ring1B and has been suggested to assist PRC localization to their targets. RYBP, firstly identified as a direct interactor with Ring1A, acts as transcriptional repressor in reporter assays, both in tissue culture cells and in the fly [PMID:16125914] Protocols Product Specific Protocols FC protocol for CL Plus 488 RYBP antibody CL488-68130 Download protocol Standard Protocols Click here to view our Standard Protocols
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