CD62L Polyclonal antibody 26477-1-AP proteintech
$149.00
In stock
SKU
26477-1-AP
| Catalog Number | 26477-1-AP |
| Synonyms | L-selectin / CD62L, L-selectin, CD62 antigen-like family member L, gp90 MEL, gp90-MEL |
| Host | Rabbit |
| Reactivity | human and More (1) |
| Reactivity | human, mouse |
| Form | Liquid |
| Formulation | PBS, Azide, Glycerol |
| Applications | WB, IHC, IF-P, ELISA |
| Applications | IF-P, ELISA |
| Host / Isotype | Rabbit / IgG |
| Tested Applications — Positive IF-P detected in | human tonsillitis tissue |
| Recommended Dilutions — Immunofluorescence (IF)-P | IF-P : 1:50-1:500 |
| Positive IF-P detected in | human tonsillitis tissue |
| Immunofluorescence (IF)-P | IF-P : 1:50-1:500 |
| Tested Reactivity | human |
| Cited Reactivity | human, mouse |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | CatNo: Ag24063 Product name: Recombinant human SELL protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 233-375 aa of BC020758 Sequence: SSQCAFSCSEGTNLTGIEETTCGPFGNWSSPEPTCQVIQCEPLSAPDLGIMNCSHPLASFSFTSACTFICSEGTELIGKKKTICESSGIWSNPSPICQKLDKSFSMIKEGDYNPLFIPVAVMVTAFSGLAFIIWLARRLKKGM Predict reactive species |
| Full Name | selectin L |
| Calculated Molecular Weight | 42 kDa |
| GenBank Accession Number | BC020758 |
| Gene Symbol | CD62L |
| Gene ID (NCBI) | 6402 |
| ENSEMBL Gene ID | ENSG00000188404 |
| RRID | AB_2880531 |
| Conjugate | Unconjugated |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | P14151 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA. |
| IF protocol for CD62L antibody 26477-1-AP | Download protocol |
| human | IHC Hum Cell Deciphering the immunological landscape of HR + metastatic breast cancer: insights from single-cell transcriptomics. Authors - Lifang He View Article |
| mouse | WB ACS Nano Charge-Adaptive Nanoparticle Attenuates Inflammation via Targeting Neutrophil Extracellular Traps (NETs) and Breaking NETs-Macrophage Crosstalk. Authors - Yang Chen View Article |
| Citations | 10 |
| Dilutions | IF-P : 1:50-1:500 |
| Isotype | IgG |
| Clonality | Polyclonal |
| Clone Number | - |
| Conjugation | Unconjugated |
CD62L, also known as L-selectin or SELL, is a member of the selectin family of adhesion molecules that also include CD62E (E-selectin) and CD62P (P-selectin) (PMID: 2663882, 2473156, 1382078). CD62L is a highly glycosylated protein of 95-105 kDa on neutrophils and 74 kDa on lymphocytes (PMID: 1382078; 1694883, 1695155). CD62L is expressed on the surface of most leukocytes, including lymphocytes, neutrophils, monocytes, eosinophils, hematopoietic progenitor cells, and immature thymocytes (PMID: 1694883, 1688580). It mediates the binding of lymphocytes to high endothelial venules (HEV) of peripheral lymph nodes through interactions with a constitutively expressed ligand, and is also involved in lymphocyte, neutrophil, and monocyte attachment to endothelium at sites of inflammation (PMID: 1382078). Protocols Product Specific Protocols IF protocol for CD62L antibody 26477-1-AP Download protocol Standard Protocols Click here to view our Standard Protocols
Publications
- Diethylaminoethyl-dextran and monocyte cell membrane coated 1,8-cineole delivery system for intracellular delivery and synergistic treatment of atherosclerosis
Journal: Int J Biol Macromol | Authors: Feng Jiang | Species: human | Application: WB - Self-Assembly Catalase Nanocomplex Conveyed by Bacterial Vesicles for Oxygenated Photodynamic Therapy and Tumor Immunotherapy.
Journal: Int J Nanomedicine | Authors: Jiayu Zhang | Species: mouse - Transcriptome-Based Network Analysis Unveils Eight Immune-Related Genes as Molecular Signatures in the Immunomodulatory Subtype of Triple-Negative Breast Cancer.
Journal: Front Oncol | Authors: Jinguo Zhang | Species: human | Application: IHC - B cells disrupt tertiary lymphoid structure formation and suppress anti-tumor immunity.
Journal: Cancer Cell | Authors: Changhao Chen | Species: human | Application: WB - Deciphering the immunological landscape of HR + metastatic breast cancer: insights from single-cell transcriptomics.
Journal: Hum Cell | Authors: Lifang He | Species: human | Application: IHC - Charge-Adaptive Nanoparticle Attenuates Inflammation via Targeting Neutrophil Extracellular Traps (NETs) and Breaking NETs-Macrophage Crosstalk.
Journal: ACS Nano | Authors: Yang Chen | Species: mouse | Application: WB
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