SESN1 Recombinant monoclonal antibody, PBS Only 86008-1-PBS proteintech
$699.00
In stock
SKU
86008-1-PBS
| Catalog Number | 86008-1-PBS |
| Synonyms | EC:1.11.1.-, p53 regulated protein PA26, p53-regulated protein PA26, PA26, SEST1 |
| Host | Rabbit |
| Reactivity | human |
| Form | Liquid |
| Formulation | PBS Only |
| Applications | WB, Indirect ELISA |
| Host / Isotype | Rabbit / IgG |
| Tested Reactivity | human |
| Class | Recombinant |
| Type | Antibody |
| Immunogen | CatNo: Ag16462 Product name: Recombinant human SESN1 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 1-141 aa of BC112036 Sequence: MAEGENEVRWDGLCSRDSTTRETALENIRQTILRKTEYLRSVKETPHRPSDGLSNTESSDGLNKLLAHLLMLSKRCPFKDVREKSEFILKSIQELGIRIPRPLGQGPSRFIPEKEILQVGSEDAQMHALFADSFAALGRLD Predict reactive species |
| Full Name | sestrin 1 |
| Calculated Molecular Weight | 551 aa, 64 kDa |
| Observed Molecular Weight | 66 kDa |
| GenBank Accession Number | BC112036 |
| Gene Symbol | SESN1 |
| Gene ID (NCBI) | 27244 |
| RRID | AB_3744544 |
| Conjugate | Unconjugated |
| Purification Method | Protein A purification |
| UNIPROT ID | Q9Y6P5 |
| Storage Buffer | PBS only, pH 7.3. |
| Storage Conditions | Store at -80°C. |
| Citations | - |
| Isotype | IgG |
| Clonality | Recombinant |
| Clone Number | 250470G1 |
| Conjugation | Unconjugated |
Sestrins, including sestrin-1 (PA26), sestrin-2 (Hi95), and sestrin-3, are 48 to 65 kDa cystein sulfinyl reductases and they modulate peroxide signaling and antioxidant defense. These proteins selectively reduce or repair hyperoxidized forms of typical 2-Cys peroxiredoxins within eukaryotes. Expression of these proteins is regulated by p53, a tumor suppressor protein. Sestrin 1 is implicated in the inhibition of cell growth. It is approximately a 66kDa protein in humans (551 amino acids).
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