SGOL2 Polyclonal antibody 30867-1-AP proteintech
$149.00
In stock
SKU
30867-1-AP
| Catalog Number | 30867-1-AP |
| Synonyms | FLJ25211, SGO2, SGOL2, Shugoshin 2, Shugoshin like 2, shugoshin like 2 (S. pombe), TRIPIN |
| Host | Rabbit |
| Reactivity | Human, mouse |
| Reactivity | human, mouse |
| Form | Liquid |
| Formulation | PBS, Azide, Glycerol |
| Applications | WB, IHC, IF/ICC, ELISA |
| Host / Isotype | Rabbit / IgG |
| Tested Applications — Positive WB detected in | HT-1080 cells, HeLa cells, U2OS cells |
| Tested Applications — Positive IHC detected in | mouse testis tissue Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0 |
| Tested Applications — Positive IF/ICC detected in | A431 cells |
| Recommended Dilutions — Western Blot (WB) | WB : 1:500-1:2000 |
| Recommended Dilutions — Immunohistochemistry (IHC) | IHC : 1:50-1:500 |
| Recommended Dilutions — Immunofluorescence (IF)/ICC | IF/ICC : 1:200-1:800 |
| Positive WB detected in | HT-1080 cells, HeLa cells, U2OS cells |
| Positive IHC detected in | mouse testis tissue Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0 |
| Positive IF/ICC detected in | A431 cells |
| Western Blot (WB) | WB : 1:500-1:2000 |
| Immunohistochemistry (IHC) | IHC : 1:50-1:500 |
| Immunofluorescence (IF)/ICC | IF/ICC : 1:200-1:800 |
| Tested Reactivity | Human, mouse |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | CatNo: Ag29656 Product name: Recombinant human SGOL2 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 1-232 aa of BC092412 Sequence: MECPVMETDSLFTSGIKRHLKDKRISKTTKLNVSLASKIKTKILNNSSIFKISLKHNNRALAQALSREKENSRRITTEKMLLQKEVEKLNFENTFLRLKLNNLNKKLIDIEALMNNNLITAIEMSSLSEFHQSSFLLSASKKKRISKQCKLMRLPFARVPLTSNDDEDEDKEKMQCDNNIKSKTLPDIPSSGSTTQPLSTQDNSEVLFLKENNQNVYGLDDSEHISSIVDVP Predict reactive species |
| Full Name | shugoshin-like 2 (S. pombe) |
| Calculated Molecular Weight | 1265 aa, 145 kDa |
| Observed Molecular Weight | 180 kDa |
| GenBank Accession Number | BC092412 |
| Gene Symbol | SGOL2 |
| Gene ID (NCBI) | 151246 |
| RRID | AB_3669770 |
| Conjugate | Unconjugated |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | Q562F6 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA. |
| IF protocol for SGOL2 antibody 30867-1-AP | Download protocol |
| IHC protocol for SGOL2 antibody 30867-1-AP | Download protocol |
| WB protocol for SGOL2 antibody 30867-1-AP | Download protocol |
| Citations | 2 |
| Dilutions | WB : 1:500-1:2000 IHC : 1:50-1:500 IF/ICC : 1:200-1:800 |
| Isotype | IgG |
| Clonality | Polyclonal |
| Clone Number | - |
| Conjugation | Unconjugated |
SGOL2 (Shugoshin 2, also known as SGO2), which is tightly involved in the cell cycle process, has been reported to protect cohesion, sustain the linkage of chromosomes, and regulate kinetochore-microtubule attachment in meiosis and mitosis (PMID: 21273764). SGOL2 has been reported as a differentially expressed gene in various types of cancer, including glioma, hepatocellular cancer, and endometrial cancer (PMID: 36566018). Protocols Product Specific Protocols IF protocol for SGOL2 antibody 30867-1-AP Download protocol IHC protocol for SGOL2 antibody 30867-1-AP Download protocol WB protocol for SGOL2 antibody 30867-1-AP Download protocol Standard Protocols Click here to view our Standard Protocols
Publications
- Elevated SGO2 expression in lung adenocarcinoma promotes migration and invasion via MAD2 and correlates with poor prognosis
Journal: Sci Rep | Authors: Min Sun - Cycloechinulin inhibits breast cancer progression via the SGOL2/METTL3/ICAM2 signaling axis and suppresses the growth of breast cancer patient-derived organoids.
Journal: Cell Signal | Authors: Shuxin Liu
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