| Catalog Number | 13492-1-AP |
| Synonyms | Sorting nexin-16, sorting nexin 16 |
| Host | Rabbit |
| Reactivity | human |
| Form | Liquid |
| Formulation | PBS, Azide, Glycerol |
| Applications | WB, IF/ICC, ELISA |
| Host / Isotype | Rabbit / IgG |
| Tested Applications — Positive WB detected in | Jurkat cells, Raji cells, U-251 cells |
| Tested Applications — Positive IF/ICC detected in | HT-29 cells |
| Recommended Dilutions — Western Blot (WB) | WB : 1:500-1:1000 |
| Recommended Dilutions — Immunofluorescence (IF)/ICC | IF/ICC : 1:200-1:800 |
| Positive WB detected in | Jurkat cells, Raji cells, U-251 cells |
| Positive IF/ICC detected in | HT-29 cells |
| Western Blot (WB) | WB : 1:500-1:1000 |
| Immunofluorescence (IF)/ICC | IF/ICC : 1:200-1:800 |
| Tested Reactivity | human |
| Cited Reactivity | human |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | CatNo: Ag4315 Product name: Recombinant human SNX16 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 1-344 aa of BC033630 Sequence: MATPYVPVPMPIGNSASSFTTNRNQRSSSFGSVSTSSNSSKGQLEDSNMGNFKQTSVPDQMDNTSSVCSSPLIRTKFTGTASSIEYSTRPRDTEEQNPETVNWEDRPSTPTILGYEVMEERAKFTVYKILVKKTPEESWVVFRRYTDFSRLNDKLKEMFPGFRLALPPKRWFKDNYNADFLEDRQLGLQAFLQNLVAHKDIANCLAVREFLCLDDPPGPFDSLEESRAFCETLEETNYRLQKELLEKQKEMESLKKLLSEKQLHIDTLENRIRTLSLEPEESLDVSETEGEQILKVESSALEVDQDVLDEESRADNKPCLSFSEPENAVSEIEVAEVAYDAEED Predict reactive species |
| Full Name | sorting nexin 16 |
| Calculated Molecular Weight | 344 aa, 39 kDa |
| Observed Molecular Weight | 39-50 kDa |
| GenBank Accession Number | BC033630 |
| Gene Symbol | SNX16 |
| Gene ID (NCBI) | 64089 |
| RRID | AB_3085416 |
| Conjugate | Unconjugated |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | P57768 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA. |
| IF protocol for SNX16 antibody 13492-1-AP | Download protocol |
| WB protocol for SNX16 antibody 13492-1-AP | Download protocol |
| human | WB Brain Behav Immun TAS2R46 activation protects intestinal barrier from chronic high glucose. Authors - Jiang-Meng Wang View Article |
| Citations | 1 |
| Dilutions | WB : 1:500-1:1000 IF/ICC : 1:200-1:800 |
| Isotype | IgG |
| Clonality | Polyclonal |
| Clone Number | - |
| Conjugation | Unconjugated |
SNX16,Sorting nexin 16, is a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which mediates membrane association by interaction with phosphoinositides. SNX16 associates with late endosome membranes as is involved in tubule formation, cholesterol transport, and transport of tetraspanin CD81. It also inhibits cell migration and tumorigenesis. SNX16 directs the sorting of EGFR to the endosomal compartment and thus regulates EGF-induced cell signaling (PMID:15292396). It may function in the trafficking of proteins between the early and late endosomal compartments. SNX16 was detected 49-53 kDa in human (PMID:12813048). Protocols Product Specific Protocols IF protocol for SNX16 antibody 13492-1-AP Download protocol WB protocol for SNX16 antibody 13492-1-AP Download protocol Standard Protocols Click here to view our Standard Protocols
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