SPP2 Polyclonal antibody 30922-1-AP proteintech
$149.00
In stock
SKU
30922-1-AP
| Catalog Number | 30922-1-AP |
| Synonyms | SPP24, Spp 24, Secreted phosphoprotein 24, Secreted phosphoprotein 2 |
| Host | Rabbit |
| Reactivity | human |
| Form | Liquid |
| Formulation | PBS, Azide, Glycerol |
| Applications | WB, ELISA |
| Host / Isotype | Rabbit / IgG |
| Tested Applications — Positive WB detected in | human placenta tissue |
| Recommended Dilutions — Western Blot (WB) | WB : 1:1000-1:6000 |
| Positive WB detected in | human placenta tissue |
| Western Blot (WB) | WB : 1:1000-1:6000 |
| Tested Reactivity | human |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | CatNo: Ag29299 Product name: Recombinant human SPP2 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 30-211 aa of NM_006944 Sequence: FPVYDYDPSSLRDALSASVVKVNSQSLSPYLFRAFRSSLKRVEVLDENNLVMNLEFSIRETTCRKDSGEDPATCAFQRDYYVSTAVCRSTVKVSAQQVQGVHARCSWSSSTSESYSSEEMIFGDMLGSHKWRNNYLFGLISDESISEQFYDRSLGIMRRVLPPGNRRYPNHRHRARINTDFE Predict reactive species |
| Full Name | secreted phosphoprotein 2, 24kDa |
| Calculated Molecular Weight | 24 kDa |
| Observed Molecular Weight | 24 kDa |
| GenBank Accession Number | NM_006944 |
| Gene Symbol | SPP2 |
| Gene ID (NCBI) | 6694 |
| RRID | AB_3669785 |
| Conjugate | Unconjugated |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | Q13103 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA. |
| WB protocol for SPP2 antibody 30922-1-AP | Download protocol |
| Citations | - |
| Dilutions | WB : 1:1000-1:6000 |
| Isotype | IgG |
| Clonality | Polyclonal |
| Clone Number | - |
| Conjugation | Unconjugated |
SPP2 (Secreted phosphoprotein 24), also known as SPP24. SPP2 is a secreted phosphoprotein, which was originally isolated and purified from bovine bone density. It is widely distributed in the body, mainly produced in the liver and transported to other tissues. SPP2 is expressed in many tissues, especially in the liver. Studies have shown that the expression level of SPP2 is up-regulated in liver cirrhosis. In addition, the expression of SPP2 is significantly related to many genes, including APOA1, SLC2A2 and TTR (PMID: 38448371). SPP2 has many biological functions, including: it can inhibit the activity of cysteine protease, participate in bone formation, inhibit calcification, and regulate BMP/TGF-β signaling pathway. SPP2 may be a tumor suppressor, which inhibits the development of HCC by inhibiting BMP/TGF-β signaling pathway. The molecular weight of SPP2 is 24 kDa. Protocols Product Specific Protocols WB protocol for SPP2 antibody 30922-1-AP Download protocol Standard Protocols Click here to view our Standard Protocols
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