STAU1 Monoclonal antibody, PBS Only 61024-1-PBS proteintech
$699.00
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SKU
61024-1-PBS
| Catalog Number | 61024-1-PBS |
| Synonyms | Double-stranded RNA-binding protein Staufen homolog 1, STAU |
| Host | Mouse |
| Reactivity | human, mouse, rat, rabbit |
| Form | Liquid |
| Formulation | PBS Only |
| Applications | WB, Indirect ELISA |
| Host / Isotype | Mouse / IgG1 |
| Tested Reactivity | human, mouse, rat, rabbit |
| Class | Monoclonal |
| Type | Antibody |
| Immunogen | CatNo: Ag5573 Product name: Recombinant human STAU1 protein Source: e coli. -derived, PET28a Tag: 6*His Domain: 227-577 aa of BC050432 Sequence: GEGEGKSKKISKKNAAIAVLEELKKLPPLPAVERVKPRIKKKTKPIVKPQTSPEYGQGINPISRLAQIQQAKKEKEPEYTLLTERGLPRRREFVMQVKVGNHTAEGTGTNKKVAKRNAAENMLEILGFKVPQAQPTKPALKSEEKTPIKKPGDGRKVTFFEPGSGDENGTSNKEDEFRMPYLSHQQLPAGILPMVPEVAQAVGVSQGHHTKDFTRAAPNPAKATVTAMIARELLYGGTSPTAETILKNNISSGHVPHGPLTRPSEQLDYLSRVQGFQVEYKDFPKNNKNEFVSLINCSSQPPLISHGIGKDVESCHDMAALNILKLLSELDQQSTEMPRTGNGPMSVCGRC Predict reactive species |
| Full Name | staufen, RNA binding protein, homolog 1 (Drosophila) |
| Calculated Molecular Weight | 63 kDa |
| Observed Molecular Weight | 55-65 kDa |
| GenBank Accession Number | BC050432 |
| Gene Symbol | STAU1 |
| Gene ID (NCBI) | 6780 |
| RRID | AB_3743260 |
| Conjugate | Unconjugated |
| Purification Method | Protein G purification |
| UNIPROT ID | O95793 |
| Storage Buffer | PBS only, pH 7.3. |
| Storage Conditions | Store at -80°C. |
| Citations | - |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Clone Number | 1H1D7 |
| Conjugation | Unconjugated |
Staufen1 (STAU1)-mediated mRNA decay (SMD) degrades translationally active mRNAs that bind the double-stranded (ds)RNA binding protein STAU1 within their 3'-untranslated regions (3'UTRs) [PMID:21307942]. STAU1 can binds to stem structures and protect Dvl2 mRNA from degradation by associating with the secondary structure in the U1 region which is located at 5′ position of second U stretch in the U2 region [PMID:17510634]. It has a role in specific positioning of mRNAs at given sites in the cell by cross-linking cytoskeletal and RNA components, and in stimulating their translation at the site.
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