Serpin B3/4 Recombinant monoclonal antibody 85807-2-RR proteintech
$149.00
In stock
SKU
85807-2-RR
| Catalog Number | 85807-2-RR |
| Synonyms | SERPINB3, SERPINB3/4, Protein T4 A, Protein T4-A, SCCA-1 |
| Host | Rabbit |
| Reactivity | human |
| Form | Liquid |
| Formulation | PBS, Azide, Glycerol |
| Applications | WB, ELISA |
| Host / Isotype | Rabbit / IgG |
| Tested Applications — Positive WB detected in | HeLa cells, L02 cells, A431 cells, HaCaT cells |
| Recommended Dilutions — Western Blot (WB) | WB : 1:2000-1:10000 |
| Positive WB detected in | HeLa cells, L02 cells, A431 cells, HaCaT cells |
| Western Blot (WB) | WB : 1:2000-1:10000 |
| Tested Reactivity | human |
| Class | Recombinant |
| Type | Antibody |
| Immunogen | CatNo: Ag24846 Product name: Recombinant human SERPINB3 protein Source: e coli. -derived, PET28a Tag: 6*His Domain: 275-390 aa of BC005224 Sequence: MRETRVDLHLPRFKVEESYDLKDTLRTMGMVDIFNGDADLSGMTGSRGLVLSGVLHKAFVEVTEEGAEAAAATAVVGFGSSPTSTNEEFHCNHPFLFFIRQNKTNSILFYGRFSSP Predict reactive species |
| Full Name | serpin peptidase inhibitor, clade B (ovalbumin), member 3 |
| Calculated Molecular Weight | 390 aa, 45 kDa |
| Observed Molecular Weight | 45 kDa |
| GenBank Accession Number | BC005224 |
| Gene Symbol | SERPINB3 |
| Gene ID (NCBI) | 6317 |
| RRID | AB_3744391 |
| Conjugate | Unconjugated |
| Purification Method | Protein A purification |
| UNIPROT ID | P29508 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA. |
| WB protocol for Serpin B3/4 antibody 85807-2-RR | Download protocol |
| Citations | - |
| Dilutions | WB : 1:2000-1:10000 |
| Isotype | IgG |
| Clonality | Recombinant |
| Clone Number | 250057B3 |
| Conjugation | Unconjugated |
Squamous cell carcinoma antigens 1 and 2 (SCCA1 and 2, SERPIN B3 and B4) are members of the ovalbumin family of serine proteinase inhibitors. SCCA1 and SCCA2 are highly homologous proteins, 91% identical at the amino acid level, and probably evolving from a common ancestor gene. The neutral form of SCCA (SCCA1, or SERPINB3) is detected in the cytoplasm of normal and some malignant squamous cells, whereas the acidic form (SCCA2, or SERPINB4) is expressed primarily in malignant cells and is the major form found in the plasma of cancer patients. SCCA2 (SERPINB4), along with SCCA1(SERPINB3), can be processed into smaller fragments that aggregate to form an autoantigen in psoriasis, probably by causing chronic inflammation. This antibody can recognize both SerpinB3 and SerpinB4. Protocols Product Specific Protocols WB protocol for Serpin B3/4 antibody 85807-2-RR Download protocol Standard Protocols Click here to view our Standard Protocols
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