CoraLite®594-conjugated TEX14 Monoclonal antibody CL594-67982 proteintech
$479.00
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SKU
CL594-67982
| Catalog Number | CL594-67982 |
| Synonyms | SGK307, SGK307, Sugen kinase 307, testis expressed 14, Testis expressed protein 14, Testis expressed sequence 14, TEX14 |
| Host | Mouse |
| Reactivity | Human, mouse, rat, rabbit |
| Reactivity | human, mouse, rat, rabbit |
| Form | Liquid |
| Formulation | PBS, Proclin300, BSA, Glycerol |
| Applications | IF-P |
| Host / Isotype | Mouse / IgG2a |
| Tested Applications — Positive IF-P detected in | mouse testis tissue |
| Recommended Dilutions — Immunofluorescence (IF)-P | IF-P : 1:50-1:500 |
| Positive IF-P detected in | mouse testis tissue |
| Immunofluorescence (IF)-P | IF-P : 1:50-1:500 |
| Tested Reactivity | Human, mouse, rat, rabbit |
| Class | Monoclonal |
| Type | Antibody |
| Immunogen | CatNo: Ag13143 Product name: Recombinant human TEX14 protein Source: e coli. -derived, PET28a Tag: 6*His Domain: 1149-1497 aa of BC040526 Sequence: QPVRSTEDEQEETSKESPKELKEKDISLTDIQDLSSISYEPDSSFKEASCKTPKINHAPTSVSTPLSPGSVSSAASQYKDCLESITFQVKTEFASCWNSQEFIQTLSDDFISVRERAKKLDSLLTSSETPPSRLTGLKRLSSFIGAGSPSLVKACDSSPPHATQRRSLPKVEAFSQHHIDELPPPSQELLDDIELLKQQQGSSTVLHENTASDGGGTANDQRHLEEQETDSKKEDSSMPLSKETEDLGEDTERAHSTLDEDLERWLQPPEESVELQDLPKGSERETNIKDQKVGEEKRKREDSITPERRKSEGVLGTSEEDELKSCFWKRLGWSESSRIIVLDQSDLSD Predict reactive species |
| Full Name | testis expressed 14 |
| Calculated Molecular Weight | 957aa,107 kDa; 1497aa,168 kDa |
| Observed Molecular Weight | 180 kDa |
| GenBank Accession Number | BC040526 |
| Gene Symbol | TEX14 |
| Gene ID (NCBI) | 56155 |
| RRID | AB_2923937 |
| Conjugate | CoraLite®594 Fluorescent Dye |
| Excitation/Emission Maxima Wavelengths | 588 nm / 604 nm |
| Excitation Laser | Yellow-Green Laser (561 nm) |
| Purification Method | Protein A purification |
| UNIPROT ID | Q8IWB6 |
| Storage Buffer | PBS with 50% glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3. |
| Storage Conditions | Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. |
| IF protocol for CL594 TEX14 antibody CL594-67982 | Download protocol |
| Citations | - |
| Dilutions | IF-P : 1:50-1:500 |
| Isotype | IgG2a |
| Clonality | Monoclonal |
| Clone Number | 1A11D6 |
| Conjugation | CoraLite®594 |
Tex14 is required both for the formation of intercellular bridges during meiosis and for kinetochore-microtubule attachment during mitosis. Intercellular bridges are evolutionarily conserved structures that connect differentiating germ cells and are required for spermatogenesis and male fertility. Tex14 acts by promoting the conversion of midbodies into intercellular bridges via its interaction with CEP55: interaction with CEP55 inhibits the interaction between CEP55 and PDCD6IP/ALIX and TSG101, blocking cell abscission and leading to transform midbodies into intercellular bridges.Tex14 also plays a role during mitosis: recruited to kinetochores by PLK1 during early mitosis and regulates the maturation of the outer kinetochores and microtubule attachment. Protocols Product Specific Protocols IF protocol for CL594 TEX14 antibody CL594-67982 Download protocol Standard Protocols Click here to view our Standard Protocols
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