CoraLite® Plus 488-conjugated TFPI Monoclonal antibody CL488-66842 proteintech
$479.00
In stock
SKU
CL488-66842
| Catalog Number | CL488-66842 |
| Synonyms | 1B12F11, EPI, Extrinsic pathway inhibitor, LACI, Lipoprotein-associated coagulation inhibitor |
| Host | Mouse |
| Reactivity | human |
| Form | Liquid |
| Formulation | PBS, Proclin300, BSA, Glycerol |
| Applications | IF/ICC, FC (Intra) |
| Host / Isotype | Mouse / IgG2a |
| Tested Applications — Positive IF/ICC detected in | HepG2 cells |
| Tested Applications — Positive FC (Intra) detected in | HepG2 cells |
| Recommended Dilutions — Immunofluorescence (IF)/ICC | IF/ICC : 1:50-1:500 |
| Recommended Dilutions — Flow Cytometry (FC) (INTRA) | FC (INTRA) : 0.40 ug per 10^6 cells in a 100 µl suspension |
| Positive IF/ICC detected in | HepG2 cells |
| Positive FC (Intra) detected in | HepG2 cells |
| Immunofluorescence (IF)/ICC | IF/ICC : 1:50-1:500 |
| Flow Cytometry (FC) (INTRA) | FC (INTRA) : 0.40 ug per 10^6 cells in a 100 µl suspension |
| Tested Reactivity | human |
| Class | Monoclonal |
| Type | Antibody |
| Immunogen | CatNo: Ag14980 Product name: Recombinant human TFPI protein Source: e coli. -derived, PET28a Tag: 6*His Domain: 29-208 aa of BC015514 Sequence: DSEEDEEHTIITDTELPPLKLMHSFCAFKADDGPCKAIMKRFFFNIFTRQCEEFIYGGCEGNQNRFESLEECKKMCTRDNANRIIKTTLQQEKPDFCFLEEDPGICRGYITRYFYNNQTKQCERFKYGGCLGNMNNFETLEECKNICEDGPNGFQVDNYGTQLNAVNNSLTPQSTKVPSL Predict reactive species |
| Full Name | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) |
| Calculated Molecular Weight | 251aa,29 kDa; 304aa,35 kDa |
| Observed Molecular Weight | 35-38 kDa |
| GenBank Accession Number | BC015514 |
| Gene Symbol | TFPI |
| Gene ID (NCBI) | 7035 |
| RRID | AB_2934500 |
| Conjugate | CoraLite® Plus 488 Fluorescent Dye |
| Excitation/Emission Maxima Wavelengths | 493 nm / 522 nm |
| Excitation Laser | Blue laser (488 nm) |
| Purification Method | Protein A purification |
| UNIPROT ID | P10646 |
| Storage Buffer | PBS with 50% glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3. |
| Storage Conditions | Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. |
| FC protocol for CL Plus 488 TFPI antibody CL488-66842 | Download protocol |
| IF protocol for CL Plus 488 TFPI antibody CL488-66842 | Download protocol |
| Citations | - |
| Dilutions | IF/ICC : 1:50-1:500 FC (INTRA) : 0.40 ug per 10^6 cells in a 100 µl suspension |
| Isotype | IgG2a |
| Clonality | Monoclonal |
| Clone Number | 1B12F11 |
| Conjugation | CoraLite® Plus 488 |
Tissue factor pathway inhibitor (TFPI) is a critical anticoagulant protein present in endothelium and platelets. TFPI is produced as two major isoforms in humans, TFPIa and TFPIb that result from alternative splicing. The TFPIb isoform localizes to the endothelium surface where it is a potent inhibitor of tissue factor-factor VIIa complexes that initiate blood coagulation. The TFPIa isoform is present in platelets. TFPI is a Kunitz-type serine protease inhibitor that exerts anticoagulant activity by blocking early procoagulant stimulia. TFPI can enhance anti-thrombotic treatment in sepsis, inflammatory diseases, and cardiovascular diseases. Protocols Product Specific Protocols FC protocol for CL Plus 488 TFPI antibody CL488-66842 Download protocol IF protocol for CL Plus 488 TFPI antibody CL488-66842 Download protocol Standard Protocols Click here to view our Standard Protocols
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