TMEM41B Recombinant monoclonal antibody, PBS Only 84510-4-PBS proteintech
$699.00
In stock
SKU
84510-4-PBS
| Catalog Number | 84510-4-PBS |
| Synonyms | Transmembrane protein 41B, KIAA0033, 242017C11 |
| Host | Rabbit |
| Reactivity | human |
| Form | Liquid |
| Formulation | PBS Only |
| Applications | WB, Indirect ELISA |
| Host / Isotype | Rabbit / IgG |
| Tested Reactivity | human |
| Class | Recombinant |
| Type | Antibody |
| Immunogen | CatNo: Ag30810 Product name: Recombinant human TMEM41B protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 1-109 aa of BC035034 Sequence: MAKGRVAERSQLGAHHTTPVGDGAAGTRGLAAPGSRDHQKEKSWVEAGSARMSLLILVSIFLSAAFVMFLVYKNFPQLSEEERVNMKVPRDMDDAKALGKVLSKYKDTF Predict reactive species |
| Full Name | transmembrane protein 41B |
| Calculated Molecular Weight | 32 kDa |
| Observed Molecular Weight | 25-28 kDa |
| GenBank Accession Number | BC035034 |
| Gene Symbol | TMEM41B |
| Gene ID (NCBI) | 440026 |
| RRID | AB_3672019 |
| Conjugate | Unconjugated |
| Purification Method | Protein A purfication |
| UNIPROT ID | Q5BJD5 |
| Storage Buffer | PBS only, pH 7.3. |
| Storage Conditions | Store at -80°C. |
| Citations | - |
| Isotype | IgG |
| Clonality | Recombinant |
| Clone Number | 242017C11 |
| Conjugation | Unconjugated |
Transmembrane protein 41B (TMEM41B), also known as Stasimon, is a major target of survival motor neuron (SMN)-dependent U12 splicing and has been identified as a protein required for motor circuit function (PMID: 23063131). TMEM41B localizes to the endoplasmic reticulum. It is involved in autophagosome biogenesis and lipid mobilization (PMID: 30126924). TMEM41B has been shown to be essential for mouse embryonic development (PMID: 30352685). Additionally, genome-scale CRISPR knockout screens reveal that TMEM41B is required for infection of flavivirus and coronavirus, including SARS-CoV-2 (PMID: 33052348; 33052332). Alternative splicing results in three transcript variants encoding distinct isoforms.
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