TRPC1 Polyclonal antibody 24727-1-AP proteintech
$149.00
In stock
SKU
24727-1-AP
| Catalog Number | 24727-1-AP |
| Synonyms | HTRP 1, Transient receptor protein 1, TRP 1, TRP1, TRPC1 |
| Host | Rabbit |
| Reactivity | human, mouse , rat |
| Reactivity | human, mouse, rat |
| Form | Liquid |
| Formulation | PBS, Azide, Glycerol |
| Applications | WB, IHC, ELISA |
| Host / Isotype | Rabbit / IgG |
| Tested Applications — Positive WB detected in | mouse brain tissue, rat brain tissue |
| Tested Applications — Positive IHC detected in | rat brain tissue Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0 |
| Recommended Dilutions — Western Blot (WB) | WB : 1:1000-1:8000 |
| Recommended Dilutions — Immunohistochemistry (IHC) | IHC : 1:50-1:500 |
| Positive WB detected in | mouse brain tissue, rat brain tissue |
| Positive IHC detected in | rat brain tissue Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0 |
| Western Blot (WB) | WB : 1:1000-1:8000 |
| Immunohistochemistry (IHC) | IHC : 1:50-1:500 |
| Tested Reactivity | human, mouse , rat |
| Cited Reactivity | human, mouse |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | CatNo: Ag16488 Product name: Recombinant human TRPC1 protein Source: e coli. -derived, T-HIS Tag: 6*His Domain: 1-349 aa of BC113953 Sequence: MMAALYPSTDLSGASSSSLPSSPSSSSPNEVMALKDVREVKEENTLNEKLFLLACDKGDYYMVKKILEENSSGDLNINCVDVLGRNAVTITIENENLDILQLLLDYGCQKLMERIQNPEYSTTMDVAPVILAAHRNNYEILTMLLKQDVSLPKPHAVGCECTLCSAKNKKDSLRHSRFRLDIYRCLASPALIMLTEEDPILRAFELSADLKELSLVEVEFRNDYEELARQCKMFAKDLLAQARNSRELEVILNHTSSDEPLDKRGLLEERMNLSRLKLAIKYNQKEFVSQSNCQQFLNTVWFGQMSGYRRKPTCKKIMTVLTVGIFWPVLSLCYLIAPKSQFGRIIHTP Predict reactive species |
| Full Name | transient receptor potential cation channel, subfamily C, member 1 |
| Calculated Molecular Weight | 793 aa, 91 kDa |
| Observed Molecular Weight | 120 kDa |
| GenBank Accession Number | BC113953 |
| Gene Symbol | TRPC1 |
| Gene ID (NCBI) | 7220 |
| RRID | AB_3085750 |
| Conjugate | Unconjugated |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | P48995 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA. |
| IHC protocol for TRPC1 antibody 24727-1-AP | Download protocol |
| WB protocol for TRPC1 antibody 24727-1-AP | Download protocol |
| human | WB Biochem Biophys Res Commun Upregulation of TRPC1 protects against high glucose-induced HUVECs dysfunction by inhibiting oxidative stress Authors - Mengting Qu View Article |
| mouse | WB J Cell Physiol Scaffold Protein PDLIM5 Regulates TRPC1 Calcium Channel Mediated Store-Operated Calcium Entry in Mouse Myoblasts. Authors - Mingyi Dong View Article |
| Citations | 2 |
| Dilutions | WB : 1:1000-1:8000 IHC : 1:50-1:500 |
| Isotype | IgG |
| Clonality | Polyclonal |
| Clone Number | - |
| Conjugation | Unconjugated |
TRPC1, also named as TRP1, belongs to the transient receptor family and STrpC subfamily. TRPC1 is thought to form a receptor-activated non-selective calcium permeant cation channel. It has been reported that the mGluR1 evoked slow EPSC is mediated by the TRPC1 cation channel. It is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Protocols Product Specific Protocols IHC protocol for TRPC1 antibody 24727-1-AP Download protocol WB protocol for TRPC1 antibody 24727-1-AP Download protocol Standard Protocols Click here to view our Standard Protocols
Publications
- Upregulation of TRPC1 protects against high glucose-induced HUVECs dysfunction by inhibiting oxidative stress
Journal: Biochem Biophys Res Commun | Authors: Mengting Qu | Species: human | Application: WB - Scaffold Protein PDLIM5 Regulates TRPC1 Calcium Channel Mediated Store-Operated Calcium Entry in Mouse Myoblasts.
Journal: J Cell Physiol | Authors: Mingyi Dong | Species: mouse | Application: WB
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