Anti-Mouse TLR4/CD284 Rabbit Recombinant Antibody, PBS Only 98018-1-PBS proteintech
$760.00
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SKU
98018-1-PBS
| Catalog Number | 98018-1-PBS |
| Synonyms | CD284, Tlr4, 230463C7, toll like receptor 4 |
| Host | Rabbit |
| Reactivity | mouse |
| Form | Liquid |
| Formulation | PBS Only |
| Applications | FC |
| Host / Isotype | Rabbit / IgG |
| Tested Reactivity | mouse |
| Class | Recombinant |
| Type | Antibody |
| Immunogen | CatNo: Ag32998 Product name: Recombinant mouse Tlr4 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 198-395 aa of NM_021297 Sequence: RENPQVNLSLDMSLNPIDFIQDQAFQGIKLHELTLRGNFNSSNIMKTCLQNLAGLHVHRLILGEFKDERNLEIFEPSIMEGLCDVTIDEFRLTYTNDFSDDIVKFHCLANVSAMSLAGVSIKYLEDVPKHFKWQSLSIIRCQLKQFPTLDLPFLKSLTLTMNKGSISFKKVALPSLSYLDLSRNALSFSGCCSYSDLG Predict reactive species |
| Full Name | toll-like receptor 4 |
| Calculated Molecular Weight | 96 kDa |
| GenBank Accession Number | NM_021297 |
| Gene Symbol | Tlr4 |
| Gene ID (NCBI) | 21898 |
| RRID | AB_3672162 |
| Conjugate | Unconjugated |
| Purification Method | Protein A purfication |
| UNIPROT ID | Q9QUK6 |
| Storage Buffer | PBS only, pH 7.3. |
| Storage Conditions | Store at -80°C. |
| Citations | - |
| Isotype | IgG |
| Clonality | Recombinant |
| Clone Number | 230463C7 |
| Conjugation | Unconjugated |
TLR4, also named as CD284, belongs to the Toll-like receptor family. TLR4 interacts with LY96 and CD14 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). TLR4 acts via MYD88, TIRAP and TRAF6, leading to NF-kB activation, cytokine secretion and the inflammatory response. Three alternatively spliced transcript variants that encode different protein isoforms have been described.