U2AF35 Monoclonal antibody, PBS Only (Detector) 60289-1-PBS proteintech
$699.00
In stock
SKU
60289-1-PBS
| Catalog Number | 60289-1-PBS |
| Synonyms | U2AF1, 2B7F11, FP793, RN, RNU2AF1 |
| Host | Mouse |
| Reactivity | human, mouse, rat |
| Form | Liquid |
| Formulation | PBS Only |
| Applications | WB, IHC, IF/ICC, FC (Intra), IP, Cytometric bead array, Indirect ELISA |
| Host / Isotype | Mouse / IgG2c |
| Tested Reactivity | human, mouse, rat |
| Class | Monoclonal |
| Type | Antibody |
| Immunogen | CatNo: Ag0399 Product name: Recombinant human U2AF35 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 26-240 aa of BC001923 Sequence: ACRHGDRCSRLHNKPTFSQTIALLNIYRNPQNSSQSADGLRCAVSDVEMQEHYDEFFEEVFTEMEEKYGEVEEMNVCDNLGDHLVGNVYVKFRREEDAEKAVIDLNNRWFNGQPIHAELSPVTDFREACCRQYEMGECTRGGFCNFMHLKPISRELRRELYGRRRKKHRSRSRSRERRSRSRDRGRGGGGGGGGGGGGRERDRRRSRDRERSGRF Predict reactive species |
| Full Name | U2 small nuclear RNA auxiliary factor 1 |
| Calculated Molecular Weight | 28 kDa |
| Observed Molecular Weight | 35-40 kDa |
| GenBank Accession Number | BC001923 |
| Gene Symbol | U2AF1 |
| Gene ID (NCBI) | 7307 |
| RRID | AB_2858277 |
| Conjugate | Unconjugated |
| Purification Method | Protein A purification |
| UNIPROT ID | Q01081 |
| Storage Buffer | PBS only, pH 7.3. |
| Storage Conditions | Store at -80°C. |
| Citations | - |
| Isotype | IgG2c |
| Clonality | Monoclonal |
| Clone Number | 2B7F11 |
| Conjugation | Unconjugated |
U2 auxiliary factor (U2AF), comprising a large and a small subunit, is a non-snRNP protein required for the binding of U2 snRNP to the pre-mRNA branch site. U2 (RNU2) small nuclear RNA auxiliary factor 1 (U2AF1,synonyms: RN, FP793, U2AF35, U2AFBP, RNU2AF1)is the small subunit which plays a critical role in both constitutive and enhancer-dependent RNA splicing by directly mediating interactions between the large subunit and proteins bound to the enhancers. The U2AF1 gene is localized to chromosome 21q22.3, which is the critical region for three diseases, progressive myoclonus epilepsy, autoimmune polyglandular disease type 1, and one form of bipolar affective disorder. The calculated molecular weight of U2AF35 is 28 kDa, but the modified U2AF35 protein is about 35-40 kDa.
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