Urocortin Polyclonal antibody 19731-1-AP proteintech
$149.00
In stock
SKU
19731-1-AP
| Catalog Number | 19731-1-AP |
| Synonyms | UCN, UI, UROC |
| Host | Rabbit |
| Reactivity | human, mouse |
| Form | Liquid |
| Formulation | PBS, Azide, Glycerol |
| Applications | WB, IHC, IP, ELISA |
| Applications | WB, IP, ELISA |
| Host / Isotype | Rabbit / IgG |
| Tested Applications — Positive WB detected in | mouse kidney tissue, HEK-293 cells, human kidney tissue, human testis tissue |
| Tested Applications — Positive IP detected in | mouse kidney tissue |
| Recommended Dilutions — Western Blot (WB) | WB : 1:500-1:3000 |
| Recommended Dilutions — Immunoprecipitation (IP) | IP : 0.5-4.0 ug for 1.0-3.0 mg of total protein lysate |
| Positive WB detected in | mouse kidney tissue, HEK-293 cells, human kidney tissue, human testis tissue |
| Positive IP detected in | mouse kidney tissue |
| Western Blot (WB) | WB : 1:500-1:3000 |
| Immunoprecipitation (IP) | IP : 0.5-4.0 ug for 1.0-3.0 mg of total protein lysate |
| Tested Reactivity | human, mouse |
| Cited Reactivity | human |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide Predict reactive species |
| Full Name | urocortin |
| Calculated Molecular Weight | 13 kDa |
| Observed Molecular Weight | 22 kDa |
| GenBank Accession Number | NM_003353 |
| Gene Symbol | UCN |
| Gene ID (NCBI) | 7349 |
| RRID | AB_10640909 |
| Conjugate | Unconjugated |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | P55089 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA. |
| IP protocol for Urocortin antibody 19731-1-AP | Download protocol |
| WB protocol for Urocortin antibody 19731-1-AP | Download protocol |
| human | WB,IHC J Cancer Res Clin Oncol Urocortin-1 promotes colorectal cancer cell migration and proliferation and inhibits apoptosis via inhibition of the p53 signaling pathway Authors - Xiaolan Guo View Article |
| Citations | 1 |
| Dilutions | WB : 1:500-1:3000 IP : 0.5-4.0 ug for IP and 0.5-4.0 ug for 1.0-3.0 mg of total protein lysate for WB |
| Isotype | IgG |
| Clonality | Polyclonal |
| Clone Number | - |
| Conjugation | Unconjugated |
Urocortin is a member of the sauvagine/corticotropin-releasing factor/urotensin I family that includes CRF, urotensin I, sauvagine, urocortin II and urocortin III. Urocortin is a potent anorexigenic peptide that induces fed-like motor activity when administered centrally or peripherally in fasted animals. Urocortin is also a potent and long-lasting hypotensive agent and increases coronary blood flow. Urocortin acts in vitro to stimulate the secretion of adrenocorticotropic hormone (ACTH) and binds with high affinity to CRF receptor types 1, 2-alpha, and 2-beta. Urocortin is synthesized as precursor, which is subsequently processed to the mature biologically active peptide (a 40-amino acid Molecule ). The 22 kDa may be a urocortin 1 precursor protein (PMID: 28887029). Protocols Product Specific Protocols IP protocol for Urocortin antibody 19731-1-AP Download protocol WB protocol for Urocortin antibody 19731-1-AP Download protocol Standard Protocols Click here to view our Standard Protocols
Publications
- Urocortin-1 promotes colorectal cancer cell migration and proliferation and inhibits apoptosis via inhibition of the p53 signaling pathway
Journal: J Cancer Res Clin Oncol | Authors: Xiaolan Guo | Species: human | Application: WB,IHC
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