WFS1 Monoclonal antibody 67291-1-Ig proteintech
$149.00
In stock
SKU
67291-1-Ig
| Catalog Number | 67291-1-Ig |
| Synonyms | 4C2B5, WFRS, WFS, WOLFRAMIN |
| Host | Mouse |
| Reactivity | human, mouse, rat, pig |
| Form | Liquid |
| Formulation | PBS, Azide, Glycerol |
| Applications | WB, ELISA |
| Host / Isotype | Mouse / IgG1 |
| Tested Applications — Positive WB detected in | HeLa cells, SH-SY5Y cells, A172 cells, HT-29 cells, HEK-293 cells, C6 cells, U-251 cells, PC-12 cells, Neuro-2a cells, SW480 cells, HepG2 cells |
| Recommended Dilutions — Western Blot (WB) | WB : 1:1000-1:5000 |
| Positive WB detected in | HeLa cells, SH-SY5Y cells, A172 cells, HT-29 cells, HEK-293 cells, C6 cells, U-251 cells, PC-12 cells, Neuro-2a cells, SW480 cells, HepG2 cells |
| Western Blot (WB) | WB : 1:1000-1:5000 |
| Tested Reactivity | human, mouse, rat, pig |
| Class | Monoclonal |
| Type | Antibody |
| Immunogen | CatNo: Ag25735 Product name: Recombinant human WFS1 protein Source: e coli. -derived, PET28a Tag: 6*His Domain: 1-95 aa of BC030130 Sequence: MDSNTAPLGPSCPQPPPAPQPQARSRLNATASLEQERSERPRAPGPQAGPGPGVRDAAAPAEPQAQHTRSRERADGTGPTKGDMEIPFEEVLERA Predict reactive species |
| Full Name | Wolfram syndrome 1 (wolframin) |
| Calculated Molecular Weight | 890 aa, 100 kDa |
| Observed Molecular Weight | 100 kDa |
| GenBank Accession Number | BC030130 |
| Gene Symbol | WFS1 |
| Gene ID (NCBI) | 7466 |
| RRID | AB_2882556 |
| Conjugate | Unconjugated |
| Purification Method | Protein G purification |
| UNIPROT ID | O76024 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA. |
| WB protocol for WFS1 antibody 67291-1-Ig | Download protocol |
| Citations | - |
| Dilutions | WB : 1:1000-1:5000 |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Clone Number | 4C2B5 |
| Conjugation | Unconjugated |
Wolfram syndrome protein (WFS1), also called wolframin, is a transmembrane protein, which is located primarily in the endoplasmic reticulum and its expression is induced in response to ER stress, partially through transcriptional activation. ER localization suggests that WFS1 protein has physiological functions in membrane trafficking, secretion, processing and/or regulation of ER calcium homeostasis. It is ubiquitously expressed with highest levels in brain, pancreas, heart, and insulinoma beta-cell lines. Mutations of the WFS1 gene are responsible for two hereditary diseases, autosomal recessive Wolfram syndrome and autosomal dominant low frequency sensorineural hearing loss. Protocols Product Specific Protocols WB protocol for WFS1 antibody 67291-1-Ig Download protocol Standard Protocols Click here to view our Standard Protocols
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