ZNF281 Polyclonal antibody 24088-1-AP proteintech
$149.00
In stock
SKU
24088-1-AP
| Catalog Number | 24088-1-AP |
| Synonyms | GC-box-binding zinc finger protein 1, GZP1, Transcription factor ZBP-99, ZBP 99, ZBP99 |
| Host | Rabbit |
| Reactivity | human |
| Form | Liquid |
| Formulation | PBS, Azide, Glycerol |
| Applications | WB, IF/ICC, ELISA |
| Host / Isotype | Rabbit / IgG |
| Tested Applications — Positive WB detected in | NCCIT cells |
| Tested Applications — Positive IF/ICC detected in | U2OS cells |
| Recommended Dilutions — Western Blot (WB) | WB : 1:500-1:1000 |
| Recommended Dilutions — Immunofluorescence (IF)/ICC | IF/ICC : 1:50-1:500 |
| Positive WB detected in | NCCIT cells |
| Positive IF/ICC detected in | U2OS cells |
| Western Blot (WB) | WB : 1:500-1:1000 |
| Immunofluorescence (IF)/ICC | IF/ICC : 1:50-1:500 |
| Tested Reactivity | human |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | CatNo: Ag21355 Product name: Recombinant human ZNF281 protein Source: e coli. -derived, PET28a Tag: 6*His Domain: 695-895 aa of BC060820 Sequence: LSSPLHNHTLFPEKQIYTTSPLECGFGQSVTSVLPSSLPKPPFGMLFGSQPGLYLSALDATHQQLTPSQELDDLIDSQKNLETSSAFQSSSQKLTSQKEQKNLESSTGFQIPSQELASQIDPQKDIEPRTTYQIENFAQAFGSQFKSGSRVPMTFITNSNGEVDHRVRTSVSDFSGYTNMMSDVSEPCSTRVKTPTSQSYR Predict reactive species |
| Full Name | zinc finger protein 281 |
| Calculated Molecular Weight | 895 aa, 97 kDa |
| Observed Molecular Weight | 110 kDa |
| GenBank Accession Number | BC060820 |
| Gene Symbol | ZNF281 |
| Gene ID (NCBI) | 23528 |
| RRID | AB_3085722 |
| Conjugate | Unconjugated |
| Purification Method | Antigen Affinity purified |
| UNIPROT ID | Q9Y2X9 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA. |
| IF protocol for ZNF281 antibody 24088-1-AP | Download protocol |
| WB protocol for ZNF281 antibody 24088-1-AP | Download protocol |
| Citations | - |
| Dilutions | WB : 1:500-1:1000 IF/ICC : 1:50-1:500 |
| Isotype | IgG |
| Clonality | Polyclonal |
| Clone Number | - |
| Conjugation | Unconjugated |
ZNF281 (zinc finger protein 281) is a Krüppel family transcription factor containing four C2H2-type zinc finger domains, located in the cell nucleus. It promotes epithelial-mesenchymal transition (EMT) and tumor metastasis by recruiting co-repressors such as CTBP or synergistically with ZEB1 to inhibit the expression of epithelial markers such as E-cadherin. Furthermore, this protein is also involved in maintaining embryonic stem cell pluripotency and regulating neural differentiation. Protocols Product Specific Protocols IF protocol for ZNF281 antibody 24088-1-AP Download protocol WB protocol for ZNF281 antibody 24088-1-AP Download protocol Standard Protocols Click here to view our Standard Protocols