| Catalog Number | CL488-85780-2 |
| Synonyms | 250708A2, double-stranded RNA |
| Host | Rabbit |
| Reactivity | n/a |
| Form | Liquid |
| Formulation | PBS, Proclin300, BSA, Glycerol |
| Applications | FC (Intra) |
| Host / Isotype | Rabbit / IgG |
| Tested Applications — Positive FC (Intra) detected in | Transfected Vero |
| Recommended Dilutions — Flow Cytometry (FC) (INTRA) | FC (INTRA) : 0.4 ug per 10^6 cells in a 100 µl suspension |
| Positive FC (Intra) detected in | Transfected Vero |
| Flow Cytometry (FC) (INTRA) | FC (INTRA) : 0.4 ug per 10^6 cells in a 100 µl suspension |
| Tested Reactivity | n/a |
| Class | Recombinant |
| Type | Antibody |
| Immunogen | dsRNA Predict reactive species |
| Full Name | dsRNA |
| RRID | AB_3747780 |
| Conjugate | CoraLite® Plus 488 Fluorescent Dye |
| Excitation/Emission Maxima Wavelengths | 493 nm / 522 nm |
| Excitation Laser | Blue laser (488 nm) |
| Purification Method | Protein A purification |
| Storage Buffer | PBS with 50% glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3. |
| Storage Conditions | Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. |
| FC protocol for CL Plus 488 dsRNA antibody CL488-85780-2 | Download protocol |
| Citations | - |
| Dilutions | FC (INTRA) : 0.4 ug per 10^6 cells in a 100 µl suspension |
| Isotype | IgG |
| Clonality | Recombinant |
| Clone Number | 250708A2 |
| Conjugation | CoraLite® Plus 488 |
dsRNA is formed by the base pairing of two RNA strands, creating a double helix structure similar to DNA, but with some differences. dsRNA can be generated through various mechanisms. In the context of viral infections, it can be derived from the genomes of dsRNA viruses, replication intermediates of single-stranded RNA viruses, or bidirectional transcription of certain DNA viruses. Additionally, aberrant splicing or transcriptional processes may lead to the formation of dsRNA structures. dsRNA is recognized as a pathogen-associated molecular pattern (PAMP) by the immune system. It can trigger a series of immune responses in cells, including the activation of antiviral innate immune pathways. Protocols Product Specific Protocols FC protocol for CL Plus 488 dsRNA antibody CL488-85780-2 Download protocol Standard Protocols Click here to view our Standard Protocols
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