Chemical compound m7G Monoclonal antibody, PBS Only 68302-1-PBS proteintech
$699.00
In stock
SKU
68302-1-PBS
| Catalog Number | 68302-1-PBS |
| Synonyms | 7-Methylguanosine |
| Host | Mouse |
| Reactivity | chemical compound |
| Form | Liquid |
| Formulation | PBS Only |
| Applications | IHC, Dot Blot, ELISA, Indirect ELISA |
| Host / Isotype | Mouse / IgG2b |
| Tested Reactivity | chemical compound |
| Class | Monoclonal |
| Type | Antibody |
| Immunogen | Peptide Predict reactive species |
| Full Name | m7G |
| RRID | AB_2935381 |
| Conjugate | Unconjugated |
| Purification Method | Protein A purification |
| Storage Buffer | PBS only, pH 7.3. |
| Storage Conditions | Store at -80°C. |
| Citations | - |
| Isotype | IgG2b |
| Clonality | Monoclonal |
| Clone Number | 2C3E10 |
| Conjugation | Unconjugated |
7-Methylguanosine (m7G) is a modified purine nucleoside. It is a methylated version of guanosine and when found in human urine, it may be a biomarker of some types of cancer. In the RNAs, 7-methylguanosine have been used to study and examine the reaction evolving methylguanosine. It also plays a role in mRNA as a blocking group at its 5´-end. The m7G modification actively participates in biological and pathological functions by affecting the metabolism of various RNA molecules, including messenger RNA, ribosomal RNA, microRNA, and transfer RNA. Increasing evidence indicates a critical role for m7G in human disease development, especially cancer, and aberrant m7G levels are closely associated with tumorigenesis and progression via regulation of the expression of multiple oncogenes and tumor suppressor genes. Protocol for Dot Blot: https://www.ptglab.com/protocol/68302-1-IgDotBlot.pdf
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