HumanKine® recombinant human EGF protein HZ-1326 proteintech
$44.00
In stock
SKU
HZ-1326
| Purity | >95% |
| Specific Activity | minimally 1.00x10 6 IU/mg |
| Formulation | United States |
| Formulation | 1x PBS, See Certificate of Analysis for details |
| Endotoxin | <1.0 EU/µg |
| Reconstitution | Briefly centrifuge the vial before opening. It is recommended to reconstitute the protein to 0.2 mg/mL in sterile 1x PBS pH 7.4 containing 0.1% endotoxin-free recombinant human serum albumin (HSA). Gently swirl or tap vial to mix. |
| Host / Isotype | Urogastrone |
| GeneID | 1950 |
| Expression | HEK293 |
| Activity(Primary) | 0.1-0.6 ng/mL |
| Accession Number | P01133 |
| Molecular Mass | 6 kDa reduced, 10 kDa non-reduced, monomer, glycosylated |
| Species Reactivity | human |
| Stability and Storage | Product Form Temperature Conditions Storage Time (From Date of Receipt) |
| Lyophilized | Room Temperature 2 weeks |
| Reconstituted as per CofA | 4°C 1 week |
| mouse | Am J Physiol Renal Physiol A conditionally immortalized Gli1-positive kidney mesenchymal cell line models myofibroblast transition Authors - Eoghainín Ó hAinmhire View Article |
| human | Cancer Med Integrated analysis based on vesicle trafficking-related genes identifying CNIH4 as a novel therapeutic target for glioma Authors - Zhen Fang View Article |
| FH Shriya (Verified Customer) (12-10-2025) | EGF protein Applications: Cell culture |
| FH Alicia (Verified Customer) (11-04-2025) | I use it for cortical organoids derived from human iPSC. It helps for neural precursor cells production. Applications: Cell culture Cell Tissue Type: Cortical organoid |
| FH Christin (Verified Customer) (12-11-2024) | Generation and maintenance of human iPSC-derived colon organoids using Crespo protocol (2017) Applications: Cell culture Cell Tissue Type: Human iPSC-derived colon organoids |
| FH Hariam (Verified Customer) (12-06-2024) | Used for blood vessel spheroids derived from human iPSCs. We assume it works since the spheroids expressed the right markers. The price is very fair as well Applications: Cell culture Cell Tissue Type: iPSC-derived blood vessel spheroids |
| FH K. (Verified Customer) (10-26-2023) | Used it in 100-500ng concentration for 10-30 minutes to check EGFR activation and always worked well. Applications: Western Blot, Immunofluorescence, Cell culture Primary Antibody Dilution: 200ng Cell Tissue Type: Human Liver cells |
Publications
- Varying mechanical forces drive sensory epithelium formation
Journal: Sci Adv | Authors: Mingyu Xia | Species: mouse | Application: Sci Adv Varying mechanical forces drive sensory epithelium formation Authors - Mingyu Xia View Article - Pharmacological blockade of TEAD–YAP reveals its therapeutic limitation in cancer cells
Journal: Nat Commun | Authors: Yang Sun | Species: mouse | Application: Nat Commun Pharmacological blockade of TEAD–YAP reveals its therapeutic limitation in cancer cells Authors - Yang Sun View Article - Pleckstrin-2 promotes the progression of colorectal cancer via YTHDF2-mediated TYMS mRNA stability
Journal: Cell Mol Life Sci | Authors: Qian Zhou | Application: Cell Mol Life Sci Pleckstrin-2 promotes the progression of colorectal cancer via YTHDF2-mediated TYMS mRNA stability Authors - Qian Zhou View Article - USP7 regulates growth and maintains the stemness of p53-mutant colorectal cancer cells via stabilizing of mutant p53
Journal: Front Oncol | Authors: Xue Li | Application: Front Oncol USP7 regulates growth and maintains the stemness of p53-mutant colorectal cancer cells via stabilizing of mutant p53 Authors - Xue Li View Article - A conditionally immortalized Gli1-positive kidney mesenchymal cell line models myofibroblast transition
Journal: Am J Physiol Renal Physiol | Authors: Eoghainín Ó hAinmhire | Species: mouse | Application: Am J Physiol Renal Physiol A conditionally immortalized Gli1-positive kidney mesenchymal cell line models myofibroblast transition Authors - Eoghainín Ó hAinmhire View Article - Integrated analysis based on vesicle trafficking-related genes identifying CNIH4 as a novel therapeutic target for glioma
Journal: Cancer Med | Authors: Zhen Fang | Species: human | Application: Cancer Med Integrated analysis based on vesicle trafficking-related genes identifying CNIH4 as a novel therapeutic target for glioma Authors - Zhen Fang View Article - Cholangiocyte ciliary defects induce sustained epidermal growth factor receptor signaling
Journal: Hepatology | Authors: Kishor Pant | Species: rat | Application: Cell treatment - PNKP targeting engages the autophagic machinery through STING and STAT3 to potentiate ferroptosis and chemotherapy in TNBC
Journal: Redox Biol | Authors: Avi Maimon | Species: mouse | Application: Cell treatment - M2 macrophage-secreted KYNU promotes stemness remodeling and malignant behavior in endometrial cancer via the SOD2-mtROS-ERO1α-UPRER axis
Journal: J Exp Clin Cancer Res | Authors: Xin Pan - Dual targeting CDK4/6 and CDK7 augments tumor response and anti-tumor immunity in breast cancer models
Journal: J Clin Invest | Authors: Sungsoo Kim - Targeting PTBP3-Mediated Alternative Splicing of COX11 Induces Cuproptosis for Inhibiting Gastric Cancer Peritoneal Metastasis
Journal: Adv Sci (Weinh) | Authors: Yajing Zhou | Species: human - Integration of Functional Human Auditory Neural Circuits Based on a 3D Carbon Nanotube System
Journal: Adv Sci (Weinh) | Authors: Yiyun Lou | Species: human - Varying mechanical forces drive sensory epithelium formation
Journal: Sci Adv | Authors: Mingyu Xia | Species: mouse - Dissecting endometrial cancer complexity in response to standard and targeted therapies.
Journal: Cell Death Dis | Authors: Sebastiano Vaccarella | Species: human - The CDK4/6 inhibitor dalpiciclib augments the antitumor efficacy of enzalutamide in preclinical models of castration-resistant prostate cancer through inhibition of MCM4-mediated DNA replication.
Journal: Cell Death Dis | Authors: Yue Liu - Transcriptome reprogramming through alternative splicing triggered by apigenin drives cell death in triple-negative breast cancer
Journal: Cell Death Dis | Authors: Meenakshi Sudhakaran | Species: human - YY1-glycolytic axis promotes high glucose-induced cancer stemness in endometrial cancer: A multi-omics guided therapeutic strategy.
Journal: Cancer Lett | Authors: Xiao Yang | Species: human - DUSP3 restrains the progression and stemness property of osteosarcoma through regulating EGFR/STAT3/SOX2 axis
Journal: Int J Biol Sci | Authors: Zhun Wei | Species: human | Application: Cell treatment - Modified Fuzheng Yiliu Decoction chemosensitizes colorectal cancer by inhibiting cancer stem cell metabolism and stemness through CAV1/ZNF460/GRP78 signaling.
Journal: Phytomedicine | Authors: Yuling Xue | Species: human - Matrix-bound EGF promotes malignant phenotypes of breast cancer organoids in the biomimetic ECM of alginate
Journal: Mater Today Bio | Authors: Xue-Yu Chen | Species: human | Application: Cell treatment - The demethylase ALKBH5 mediates ZKSCAN3 expression through the m6A modification to activate VEGFA transcription and thus participates in MNNG-induced gastric cancer progression
Journal: J Hazard Mater | Authors: Qing Wang | Species: human - Multi-omics analysis reveals the key role of STIL in Li-Fraumeni syndrome and osteosarcoma.
Journal: NPJ Precis Oncol | Authors: Yu Qiao | Species: human | Application: Cell treatment - Mechanisms of resistance to VHL loss-induced genetic and pharmacological vulnerabilities.
Journal: EMBO Mol Med | Authors: Jianfeng Ge | Species: human - A Dynamic Silver-Sulfur/Schiff Base Hydrogel for Delivering Neural Stem Cells in Cerebral Palsy.
Journal: ACS Appl Mater Interfaces | Authors: Simiao Yu | Species: rat - Effects of long-term treatment with low concentration butylparaben on prostate organoids
Journal: Environ Pollut | Authors: Yujin Hwang - Food-derived peptide RDP3 mitigates pyroptosis to enhance oral mucosal repair via the IL-2Rβ/PI3K axis.
Journal: NPJ Regen Med | Authors: Junyuan Wang - Combinatorial phenethyl isothiocyanate and withaferin A targets multiple epigenetics pathways to inhibit MCF-7 and MDA-MB-231 human breast cancer cells
Journal: Cancer Cell Int | Authors: Mohammad Mijanur Rahman | Species: human | Application: Cell treatment - Injury-induced FoxM1 expression in mouse kidney drives epithelial proliferation by a Cyclin F dependent mechanism
Journal: JCI Insight | Authors: Megan L Noonan - Enhanced binding of β-catenin and β-TrCP mediates LMPt's anti-CSCs activity in colorectal cancer
Journal: Biochem Pharmacol | Authors: Mengyan Wang | Species: human - Pleckstrin-2 promotes the progression of colorectal cancer via YTHDF2-mediated TYMS mRNA stability
Journal: Cell Mol Life Sci | Authors: Qian Zhou | Application: Cell treatment - Apelin-13 enhances the neural differentiation of dental pulp stem cells through the Wnt/β-catenin signaling pathway.
Journal: Life Sci | Authors: Yatong Li | Species: human - Bioinspired sodium alginate/silk fibroin dual-crosslinked conductive injectable hydrogel for neural stem cell therapy in cerebral palsy.
Journal: J Mater Chem B | Authors: Simiao Yu | Species: rat - Uncovering the role of transient receptor potential channels in pterygium: a machine learning approach
Journal: Inflamm Res | Authors: Yuchen Cai | Species: human - Kaempferol Alleviates Mitochondrial Damage by Reducing Mitochondrial Reactive Oxygen Species Production in Lipopolysaccharide-Induced Prostate Organoids
Journal: Foods | Authors: Myeong Joon Lee - Sodium Alginate Silk Fibroin Hydrogel Loaded with Neural Stem Cells for Treatment of Cerebral Palsy.
Journal: Biomacromolecules | Authors: Simiao Yu | Species: rat - A tabletop blast device for the study of the long-term consequences of traumatic brain injury on brain organoids.
Journal: Cell Rep Methods | Authors: Riccardo Sirtori | Species: human - Altered Neuronal Support and Inflammatory Response in Bipolar Disorder Patient-Derived Astrocytes
Journal: Stem Cell Reports | Authors: Krishna C Vadodaria | Species: human - Establishment of Mouse Meibomian Gland Organoids for In Vitro Modeling of Meibomian Gland Dysfunction.
Journal: Invest Ophthalmol Vis Sci | Authors: Jingyu Qu | Species: mouse - Bu-Gu-Sheng-Sui decoction promotes osteogenesis via activating the ERK/Smad signaling pathways
Journal: Front Pharmacol | Authors: Ning Liu | Species: mouse | Application: Cell treatment - Fibrous corona is reduced in cancer cell lines that attenuate microtubule nucleation from kinetochores
Journal: Cancer Sci | Authors: Yudai Ishikawa - Mild hypothermia promotes neuronal differentiation of human neural stem cells via RBM3-SOX11 signaling pathway
Journal: iScience | Authors: Yuxiao Ma - Identification of Kinase Targets for Enhancing the Antitumor Activity of Eribulin in Triple-Negative Breast Cell Lines
Journal: Biomedicines | Authors: Xuemei Xie | Species: human - Unlocking personalized endometrial cancer treatment: the critical role of the BBIRE biobank in sample collection and distribution.
Journal: Front Mol Biosci | Authors: V. Bruno | Species: human | Application: Cell treatment - dCas9-HDAC8-EGFP fusion enables epigenetic editing of breast cancer cells by H3K9 deacetylation
Journal: Eur J Cell Biol | Authors: Mohammad Mijanur Rahman | Species: human - PTP4A2 Promotes Glioblastoma Progression and Macrophage Polarization Under Microenvironmental Pressure
Journal: Cancer Res Commun | Authors: Tiffanie Chouleur - Ketamine modulates neural stem cell differentiation by regulating TRPC3 expression through the GSK3β/β-catenin pathway
Journal: Neurotoxicology | Authors: Ying-Jun She | Species: rat - A conditionally immortalized Gli1-positive kidney mesenchymal cell line models myofibroblast transition
Journal: Am J Physiol Renal Physiol | Authors: Eoghainín Ó hAinmhire | Species: mouse | Application: Cell treatment - Wnt/Ca2+ pathway inhibits neural differentiation of human dental pulp stem cells in vitro
Journal: J Dent Sci | Authors: Shi-Hua Wang | Application: Cell treatment - Stemness-Relevant Gene Signature for Chemotherapeutic Response and Prognosis Prediction in Ovarian Cancer
Journal: Stem Cells Int | Authors: Kaixia Zhou | Species: human - Integrated analysis based on vesicle trafficking-related genes identifying CNIH4 as a novel therapeutic target for glioma
Journal: Cancer Med | Authors: Zhen Fang | Species: human - SLBP promotes lung adenocarcinoma progression by inhibiting ferroptosis and reprogramming glutamine metabolism via FADS2 interaction.
Journal: Exp Cell Res | Authors: Wei Yan | Species: human - The role of BHLHE40 in clinical features and prognosis value of PDAC by comprehensive analysis and in vitro validation
Journal: Front Oncol | Authors: Chao Liu - USP7 regulates growth and maintains the stemness of p53-mutant colorectal cancer cells via stabilizing of mutant p53
Journal: Front Oncol | Authors: Xue Li | Application: Cell treatment - Unveiling the Differences in Biological Properties of Dental Pulp Stem Cells from Normal and Inflamed Pulp: A Comprehensive Comparative Study.
Journal: Med Sci Monit | Authors: Shao-Chen Nie | Species: human | Application: Cell treatment - Astragaloside IV enhances the sensitivity of breast cancer stem cells to paclitaxel by inhibiting stemness
Journal: Transl Cancer Res | Authors: Ping Huang - Myofibroblast-Like CAFs in Metastatic Lymph Nodes Drive Tumor Stemness and Poor Prognosis in Head and Neck Cancer.
Journal: Cancer Sci | Authors: Hiroyuki Hagiwara | Species: human
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