HumanKine® recombinant human TPO (Thrombopoietin) protein HZ-1248 proteintech
$266.00
In stock
SKU
HZ-1248
| Purity | >95% |
| Specific Activity | >1.00 x 10 6 IU/mg |
| Formulation | United States |
| Formulation | 1x PBS, See Certificate of Analysis for details |
| Endotoxin | < 1 EU/µg |
| Reconstitution | Briefly centrifuge the vial before opening. It is recommended to reconstitute the protein in sterile 1xPBS pH 7.4 containing 0.1% endotoxin-free recombinant human serum albumin (HSA). |
| Host / Isotype | MGDF, MKCSF, ML, MPLLG, THPO, Thrombopoietin |
| GeneID | 7066 |
| Expression | HEK293 |
| Activity(Primary) | 100-500 ng/mL |
| Activity(Secondary) | 1-7 ng/mL EC50 in MO7e cells |
| Accession Number | P40225 |
| Molecular Mass | 70 to 93 kDa reduced and non-reduced, monomer, glycosylated. |
| Species Reactivity | human |
| Stability and Storage | Product Form Temperature Conditions Storage Time (From Date of Receipt) |
| Lyophilized | Room Temperature 2 weeks |
| Reconstituted as per CofA | 4°C 1 week |
| human | Oncotarget Sensitizing leukemia stem cells to NF-κB inhibitor treatment in vivo by inactivation of both TNF and IL-1 signaling. Authors - JingLi View Article |
| FH Arpita (Verified Customer) (04-15-2025) | NA Applications: Cell culture |
Publications
- PF4 activates the c-Mpl-Jak2 pathway in platelets
Journal: Blood | Authors: Richard John Buka | Species: human | Application: Blood PF4 activates the c-Mpl-Jak2 pathway in platelets Authors - Richard John Buka View Article - Co-inhibition of NF-κB and JNK is synergistic in TNF-expressing human AML.
Journal: J Exp Med | Authors: AndrewVolk | Species: human | Application: J Exp Med Co-inhibition of NF-κB and JNK is synergistic in TNF-expressing human AML. Authors - AndrewVolk View Article - β-Catenin interacts with canonical RBPs including MSI2 to associate with a Wnt signalling mRNA network in myeloid leukaemia cells
Journal: Oncogene | Authors: M Wagstaff | Species: human | Application: Oncogene β-Catenin interacts with canonical RBPs including MSI2 to associate with a Wnt signalling mRNA network in myeloid leukaemia cells Authors - M Wagstaff View Article - HCMV modulates c-Mpl/IEX-1 pathway-mediated megakaryo/thrombopoiesis via PDGFRα and αvβ3 receptors after allo-HSCT.
Journal: J Cell Physiol | Authors: Fei-Er Feng | Species: human | Application: J Cell Physiol HCMV modulates c-Mpl/IEX-1 pathway-mediated megakaryo/thrombopoiesis via PDGFRα and αvβ3 receptors after allo-HSCT. Authors - Fei-Er Feng View Article - Bioprinting of Human Cord Blood-Derived CD34+ Cells and Exploration of the Multilineage Differentiation Ability in Vitro.
Journal: ACS Biomater Sci Eng | Authors: Lidan Chen | Species: human | Application: ACS Biomater Sci Eng Bioprinting of Human Cord Blood-Derived CD34+ Cells and Exploration of the Multilineage Differentiation Ability in Vitro. Authors - Lidan Chen View Article - Sensitizing leukemia stem cells to NF-κB inhibitor treatment in vivo by inactivation of both TNF and IL-1 signaling.
Journal: Oncotarget | Authors: JingLi | Species: human | Application: Oncotarget Sensitizing leukemia stem cells to NF-κB inhibitor treatment in vivo by inactivation of both TNF and IL-1 signaling. Authors - JingLi View Article - DSUP modified mesenchymal stem cells exert significant radiation protective effect by enhancing the hematopoietic niche
Journal: Stem Cell Res Ther | Authors: Fu-Dong Chen | Species: human - The anti-leukemic effects of vitamin K4 by modulating the JAK/STAT signaling pathway.
Journal: Cancer Cell Int | Authors: Xiuyu Li | Species: human - Bioprinting of Human Cord Blood-Derived CD34+ Cells and Exploration of the Multilineage Differentiation Ability in Vitro.
Journal: ACS Biomater Sci Eng | Authors: Lidan Chen | Species: human - Sensitizing leukemia stem cells to NF-κB inhibitor treatment in vivo by inactivation of both TNF and IL-1 signaling.
Journal: Oncotarget | Authors: JingLi | Species: human | Application: Cell Culture - A 3D engineered scaffold for hematopoietic progenitor/stem cell co-culture in vitro.
Journal: Sci Rep | Authors: Dezhi Zhou | Species: human | Application: Cell treatment - HCMV modulates c-Mpl/IEX-1 pathway-mediated megakaryo/thrombopoiesis via PDGFRα and αvβ3 receptors after allo-HSCT.
Journal: J Cell Physiol | Authors: Fei-Er Feng | Species: human - cGAS/STING-mediated upregulation of NKG2D ligands in LSCs contributes to enhanced sensitivity to NK cells.
Journal: Front Oncol | Authors: Yan Ouyang | Species: human - Evaluation of the Effects of Power-Frequency Magnetic Field Exposure on B-Cell Differentiation From Human Hematopoietic Stem/Progenitor Cells
Journal: Bioelectromagnetics | Authors: Masayuki Takahashi | Species: human - Impaired lipoprotein secretion by APOE4 leads to lysosomal and mitochondrial dysfunction in human microglia.
Journal: bioRxiv | Authors: Jasmin S. Revanna
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