HumanKine® recombinant human VEGF165 protein HZ-1038 proteintech
$215.00
In stock
SKU
HZ-1038
| Purity | >95% |
| Formulation | United States |
| Formulation | 1x PBS, See Certificate of Analysis for details |
| Endotoxin | <1 EU/µg |
| Reconstitution | Briefly centrifuge the vial before opening. It is recommended to reconstitute the protein to 0.2 mg/mL in sterile 1x PBS pH 7.4 containing 0.1% endotoxin-free recombinant serum albumin (HSA). Gently swirl or tap vial to mix. |
| Host / Isotype | L VEGFA, MVCD1, Vascular permeability factor, VEGF, VEGF A, VEGF165, VEGFA, VPF |
| GeneID | 7422 |
| Expression | HEK293 |
| Activity(Primary) | 0.3-3.75 ng/mL |
| Activity(Secondary) | 0.3-0.375 |
| Accession Number | P15692-4 |
| Molecular Mass | 22 to 30 and 50 kDa reduced, 40 to 50 and 75 kDa non-reduced, homodimer, glycosylated |
| Species Reactivity | human |
| Stability and Storage | Product Form Temperature Conditions Storage Time (From Date of Receipt) |
| Lyophilized | Room Temperature 2 weeks |
| Reconstituted as per CofA | 4°C 1 week |
| human | Cell Res SIRT6 safeguards human mesenchymal stem cells from oxidative stress by coactivating NRF2. Authors - HuizePan View Article |
| FH Ryszard (Verified Customer) (03-21-2025) | I was able to use this humankine VEGF165 to great succes to generate 3D tubular structures derived from iPS cells. The powder is easy to resuspend and seems stable at 4C for almost 2 weeks. I will check for Vascular markers at somepoint but looks very promising. Applications: Cell culture Cell Tissue Type: Human iPS cells |
Publications
- Conversion of human fibroblasts to angioblast-like progenitor cells.
Journal: Nat Methods | Authors: LeoKurian | Species: human | Application: Nat Methods Conversion of human fibroblasts to angioblast-like progenitor cells. Authors - LeoKurian View Article - Single-cell transcriptomic atlas of primate cardiopulmonary aging.
Journal: Cell Res | Authors: Shuai Ma | Species: human | Application: Cell Res Single-cell transcriptomic atlas of primate cardiopulmonary aging. Authors - Shuai Ma View Article - Bioengineering an improved three-dimensional vascularized co-culture model for studying Neuron-Microglia interactions.
Journal: Bioact Mater | Authors: Yinhe Han | Species: human | Application: Bioact Mater Bioengineering an improved three-dimensional vascularized co-culture model for studying Neuron-Microglia interactions. Authors - Yinhe Han View Article - Identification of novel long noncoding RNAs underlying vertebrate cardiovascular development.
Journal: Circulation | Authors: LeoKurian | Species: human | Application: Circulation Identification of novel long noncoding RNAs underlying vertebrate cardiovascular development. Authors - LeoKurian View Article - SIRT6 safeguards human mesenchymal stem cells from oxidative stress by coactivating NRF2.
Journal: Cell Res | Authors: HuizePan | Species: human | Application: Cell Res SIRT6 safeguards human mesenchymal stem cells from oxidative stress by coactivating NRF2. Authors - HuizePan View Article - DutaFabs are engineered therapeutic Fab fragments that can bind two targets simultaneously.
Journal: Nat Commun | Authors: Roland Beckmann | Application: Nat Commun DutaFabs are engineered therapeutic Fab fragments that can bind two targets simultaneously. Authors - Roland Beckmann View Article - Targeted degradation of VEGF with bispecific aptamer-based LYTACs ameliorates pathological retinal angiogenesis
Journal: Theranostics | Authors: Ping Zhou | Species: mouse - Receptor tyrosine kinase inhibitor Sunitinib and integrin antagonist peptide HM-3 show similar lipid raft dependent biphasic regulation of tumor angiogenesis and metastasis.
Journal: J Exp Clin Cancer Res | Authors: Jialiang Hu | Species: human | Application: Cell Culture - ZFAT is essential for endothelial cell assembly and the branch point formation of capillary-like structures in an angiogenesis model.
Journal: Cell Mol Biol Lett | Authors: Yasuhiro Yoshida | Species: human | Application: Cell Culture - Targeting endosomal trafficking-mediated antigen escape to resensitize myeloma to CAR-T therapy.
Journal: J Immunother Cancer | Authors: Zhuning Wang | Species: human - Differential regulation of monocyte exhaustion by distinct TLR agonists and underlying mechanisms.
Journal: Cell Commun Signal | Authors: Jing Wang | Species: human - KTX207-mediated PDE4D degradation disrupts tumour cell migration, invasion, and angiogenic potential.
Journal: Cell Commun Signal | Authors: Alina Zorn - Metabolic reprogramming and altered ATP content impair neuroprotective functions of microglia in β-glucocerebrosidase deficiency models.
Journal: J Neuroinflammation | Authors: Electra Brunialti | Species: human - Yindan Xinnaotong Soft Capsule improves post-ischemic stroke recovery by regulating CREB/BDNF-mediated synaptic plasticity and CREB/VEGFA-mediated angiogenesis
Journal: Phytomedicine | Authors: Cuicui Cheng - Promoting the transition from pyroptosis to apoptosis in endothelial cells: a novel approach to alleviate methylglyoxal-induced vascular damage
Journal: J Transl Med | Authors: Ruqiang Yuan | Species: human - Vascular organoid model of Hutchinson-Gilford progeria syndrome uncovers repression of the SRF pathway in premature aging.
Journal: Dev Cell | Authors: Xiaoyan Sun | Species: human - HAND1 level controls the specification of multipotent cardiac and extraembryonic progenitors from human pluripotent stem cells
Journal: EMBO J | Authors: Adam T Lynch | Species: human - RhoJ integrates attractive and repulsive cues in directional migration of endothelial cells.
Journal: EMBO J | Authors: Yoko Fukushima | Species: human - Chiglitazar Activates PPAR-α/γ to Suppress Oxidative Stress and Angiogenesis in Corneal Neovascularization.
Journal: Antioxidants (Basel) | Authors: Tao Tao | Species: human - KRIT1 heterozygous mutations are sufficient to induce a pathological phenotype in patient-derived iPSC models of cerebral cavernous malformation
Journal: Cell Rep | Authors: Maximiliano Arce - Autophagy Contributes to the Maintenance of Genomic Integrity by Reducing Oxidative Stress.
Journal: Oxid Med Cell Longev | Authors: Wenqing Bu | Species: human - A vascularized 3D bioengineered lung tumor model for anticancer drug screening.
Journal: Cancer Cell Int | Authors: Mingqi Wang | Species: human - Proliferative and Osteogenic Supportive Effect of VEGF-Loaded Collagen-Chitosan Hydrogel System in Bone Marrow Derived Mesenchymal Stem Cells
Journal: Pharmaceutics | Authors: Jeevithan Elango | Species: human - Saponins from Nigella glandulifera seeds attenuate collagen-induced rheumatoid arthritis in rats via the OPG/RANKL/NF-κB and Ang/Tie-2 pathways.
Journal: J Ethnopharmacol | Authors: Hailun Jiang | Species: human - L009 Peptide as a Novel Antiangiogenic Agent for Corneal Neovascularization via Regulation of the TNFSF15-VEGF Axis
Journal: Ocul Surf | Authors: Ke Yan | Species: human - Müller glia-derived exosomal miR-9-3p promotes angiogenesis by restricting sphingosine-1-phosphate receptor S1P1 in diabetic retinopathy.
Journal: Mol Ther Nucleic Acids | Authors: Yu Liu | Species: human - Gap26 inhibited angiogenesis through the β-catenin-VE-cadherin-VEGFR2-Erk signaling pathway
Journal: Life Sci | Authors: Chuyang Xu | Species: human | Application: Cell treatment - Antiangiogenic Action of JZL184 on Endothelial Cells via Inhibition of VEGF Expression in Hypoxic Lung Cancer Cells
Journal: Cells | Authors: Felix Wittig - sVEGFR1 up-regulation via EGR1 impairs vascular repair in SFTSV-induced hemorrhage
Journal: EMBO Rep | Authors: Na Jiang - Extracellular Vesicles from Human Umbilical Cord-Derived MSCs Affect Vessel Formation In Vitro and Promote VEGFR2-Mediated Cell Survival
Journal: Cells | Authors: Ana Muñiz-García | Species: human - A small-diameter vascular graft immobilized peptides for capturing endothelial colony-forming cells
Journal: Front Bioeng Biotechnol | Authors: Yaqi Tang - Esaxerenone Inhibits Renal Angiogenesis and Endothelial-Mesenchymal Transition via the VEGFA and TGF-β1 Pathways in Aldosterone-Infused Mice
Journal: Int J Mol Sci | Authors: Xiaomeng Gao | Species: human | Application: Cell treatment - β-Caryophyllene Inhibits Endothelial Tube Formation by Modulating the Secretome of Hypoxic Lung Cancer Cells-Possible Role of VEGF Downregulation
Journal: Int J Mol Sci | Authors: Felix Wittig - Pharmacokinetics of pars plana intravitreal injections versus microcannula suprachoroidal injections of bevacizumab in a porcine model.
Journal: Invest Ophthalmol Vis Sci | Authors: Timothy WOlsen | Species: pig | Application: Cell Culture - Bevacizumab Radioimmunotherapy (RIT) with Accelerated Blood Clearance Using the Avidin Chase.
Journal: Mol Pharm | Authors: Ryan Yudistiro | Species: human | Application: Cell Culture - Vascularized cardiac tissue construction with orientation by layer-by-layer method and 3D printer.
Journal: Sci Rep | Authors: Yoshinari Tsukamoto - Bevacizumab Radioimmunotherapy (RIT) with Accelerated Blood Clearance Using the Avidin Chase.
Journal: Mol Pharm | Authors: Ryan Yudistiro | Species: human | Application: Cell Culture - Brief report: efficient generation of hematopoietic precursors and progenitors from human pluripotent stem cell lines.
Journal: Stem Cells | Authors: Niels-BjarneWoods | Species: human | Application: Cell Culture - siRASA1 in vascular endothelial cells alleviates subretinal fibrosis through inhibiting macrophage-myofibroblast transdifferentiation via SHH signaling pathway.
Journal: Cell Signal | Authors: Lei Jiang | Species: human | Application: Cell treatment - Inhibitory effects of Eplerenone on angiogenesis via modulating SGK1/TGF-β pathway in contralateral kidney of CKD pregnancy rats
Journal: Cell Signal | Authors: Wenping Zhou | Species: human - FK506 induces endothelial dysfunction through attenuation of Akt and ERK1/2 independently of calcineurin inhibition and the caspase pathway.
Journal: Cell Signal | Authors: Ryoji Eguchi | Species: human | Application: Cell Culture - GCN5 participates in KLF4-VEGFA feedback to promote endometrial angiogenesis.
Journal: iScience | Authors: Can Cao | Species: human - HucMSCs can alleviate abnormal vasculogenesis induced by high glucose through the MAPK signaling pathway
Journal: iScience | Authors: Yang Yao | Species: human | Application: Cell treatment - Therapeutic potential of targeting the NEDD4L-eEF1A1 axis in cancer therapy.
Journal: Acta Biochim Biophys Sin (Shanghai) | Authors: Yan Qin | Species: human - GCN5 participates in KLF4-VEGFA feedback to promote endometrial angiogenesis.
Journal: iScience | Authors: Can Cao | Species: human - VESNA: an open-source tool for automated 3D vessel segmentation and network analysis.
Journal: BMC Bioinformatics | Authors: Magdalena Schüttler | Species: human - Vascular endothelial growth factor promotes macrophage apoptosis through stimulation of tumor necrosis factor superfamily member 14 (TNFSF14/LIGHT).
Journal: Wound Repair Regen | Authors: Melissa L Petreaca | Species: human | Application: Cell Culture - Nuclear receptor 4A1 ameliorates renal fibrosis by inhibiting vascular endothelial growth factor A induced angiogenesis in UUO rats
Journal: Biochim Biophys Acta Mol Cell Res | Authors: Hongshuang Wang - Monocyte-Platelet Aggregates Are Major Source of BDNF after Bacterial Stimulation of Human Peripheral Blood Immune Cells.
Journal: Eur J Immunol | Authors: Fabien Sarcletti | Species: human - An Evaluation of the Replacement of Animal-derived Biomaterials in Human Primary Cell Culture
Journal: Altern Lab Anim | Authors: Laura R Bramwell | Species: human - Endothelial cell-specific molecule 1 induced by interferon tau promotes angiogenesis in bovine endothelial cells.
Journal: Theriogenology | Authors: Hayato Naito | Species: human - Parallel Regulation of von Hippel-Lindau Disease by pVHL-Mediated Degradation of B-Myb and Hypoxia-Inducible Factor α.
Journal: Mol Cell Biol | Authors: FumihikoOkumura | Application: Cell Culture - Construction of 3D cardiac tissue with synchronous powerful beating using human cardiomyocytes from human iPS cells prepared by a convenient differentiation method.
Journal: J Biosci Bioeng | Authors: Yumi Sasano | Species: human - Noninvasive OCT Imaging of Three-Dimensional Cardiac Tissues Derived from Human Induced Pluripotent Stem Cells.
Journal: J Tissue Eng Regen Med | Authors: Atsushi Miyaoka | Species: human - Supersensitive Layer-by-Layer 3D Cardiac Tissues Fabricated on a Collagen Culture Vessel Using Human-Induced Pluripotent Stem Cells.
Journal: Tissue Eng Part C Methods | Authors: Yoshinari Tsukamoto | Species: human | Application: Cell treatment - Vascular endothelial growth factor alleviates mitochondrial dysfunction and suppression of mitochondrial biogenesis in models of Alzheimer's disease.
Journal: Int J Neurosci | Authors: Xiangtian Liu | Species: human | Application: Cell Culture - Protocol for generation of endothelial cells from human-derived iPSCs and integration into mouse brain explants.
Journal: STAR Protoc | Authors: Iza Erzar | Species: human
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