ATRIP Polyclonal antibody 11327-1-AP proteintech
$149.00
In stock
SKU
11327-1-AP
| Catalog Number | 11327-1-AP |
| Synonyms | AGS 1, AGS1, ATM and Rad3-related-interacting protein, ATR-interacting protein, DRN 3 |
| Host | Rabbit |
| Reactivity | human, mouse, rat |
| Form | Liquid |
| Formulation | PBS, Azide, Glycerol |
| Applications | WB, IHC, IP, CoIP, ELISA |
| Applications | WB, IP, ELISA |
| Host / Isotype | Rabbit / IgG |
| Tested Applications — Positive WB detected in | HeLa cells, MCF-7 cells, PC-3 cells |
| Tested Applications — Positive IP detected in | HeLa cells |
| Recommended Dilutions — Western Blot (WB) | WB : 1:2000-1:16000 |
| Recommended Dilutions — Immunoprecipitation (IP) | IP : 0.5-4.0 ug for 1.0-3.0 mg of total protein lysate |
| Positive WB detected in | HeLa cells, MCF-7 cells, PC-3 cells |
| Positive IP detected in | HeLa cells |
| Western Blot (WB) | WB : 1:2000-1:16000 |
| Immunoprecipitation (IP) | IP : 0.5-4.0 ug for 1.0-3.0 mg of total protein lysate |
| Tested Reactivity | human, mouse, rat |
| Cited Reactivity | human, mouse |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | CatNo: Ag1869 Product name: Recombinant human ATRIP protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 464-765 aa of BC014153 Sequence: PEDSVCILEGFSVTALSILQHLVCHSGAVVSLLLSGVGADSAAGEGNRSLVHRLSDGDMTSALRGVADDQGQHPLLKMLLHLLAFSSAATGHLQASVLTQCLKVLVKLAENTSCDFLPRFQCVFQVLPKCLSPETPLPSVLLAVELLSLLADHDQLAPQLCSHSEGCLLLLLYMYITSRPDRVALETQWLQLEQEVVRALTVMLHRQWLTVRRAGGPPRTDQQRRTVRCLRDTVLLLHGLSQKDKLFMMHCVEVLHQFDQVMPGVSMLIRGLPDVTDCEEAALDDLCAAETDVEDPEVECG Predict reactive species |
| Full Name | ATR interacting protein |
| Calculated Molecular Weight | 791 aa, 86 kDa |
| Observed Molecular Weight | 86-90 kDa |
| GenBank Accession Number | BC014153 |
| Gene Symbol | ATRIP |
| Gene ID (NCBI) | 84126 |
| RRID | AB_10837229 |
| Conjugate | Unconjugated |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | Q8WXE1 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA. |
| IP protocol for ATRIP antibody 11327-1-AP | Download protocol |
| WB protocol for ATRIP antibody 11327-1-AP | Download protocol |
| mouse | WB Biochem J Mutation of the RelA(p65) Thr505 phosphosite disrupts the DNA replication stress response leading to CHK1 inhibitor resistance Authors - Jill E Hunter View Article |
| human | WB Cell Insight ATR/Chk1 interacting lncRNA modulates DNA damage response to induce breast cancer chemoresistance Authors - Rong Luo View Article |
| Citations | 7 |
| Dilutions | WB : 1:2000-1:16000 IP : 0.5-4.0 ug for IP and 0.5-4.0 ug for 1.0-3.0 mg of total protein lysate for WB |
| Isotype | IgG |
| Clonality | Polyclonal |
| Clone Number | - |
| Conjugation | Unconjugated |
ATRIP (ATR Interacting Protein) and ATR signalling complex is a central mediator of the replicative stress response (RSR),and mutations in both genes have been reported in Seckel syndrome. Protocols Product Specific Protocols IP protocol for ATRIP antibody 11327-1-AP Download protocol WB protocol for ATRIP antibody 11327-1-AP Download protocol Standard Protocols Click here to view our Standard Protocols
Publications
- A fluorinated peptide with high serum- and lipid-tolerence for the delivery of siRNA drugs to treat obesity and metabolic dysfunction.
Journal: Biomaterials | Authors: Jin Qiu KD Validated | Species: mouse | Application: WB,IHC - Huangkui Capsule Ameliorates Renal Fibrosis in a Unilateral Ureteral Obstruction Mouse Model Through TRPC6 Dependent Signaling Pathways.
Journal: Front Pharmacol | Authors: Li-Fei Gu | Species: human | Application: WB - Targeting AARS1-dependent lactylation improves neuronal process plasticity and mitigates cognitive deficits in sepsis-associated encephalopathy.
Journal: Brain Behav Immun | Authors: Shiyuan Luo | Species: mouse | Application: WB,IP,IHC - Phospho-TRIM21 orchestrates RPA2 ubiquitination switch to promote homologous recombination and tumor radio/chemo-resistance
Journal: Oncogene | Authors: Jie Zhang | Species: human | Application: WB,CoIP - Mutation of the RelA(p65) Thr505 phosphosite disrupts the DNA replication stress response leading to CHK1 inhibitor resistance
Journal: Biochem J | Authors: Jill E Hunter | Species: mouse | Application: WB - ATR/Chk1 interacting lncRNA modulates DNA damage response to induce breast cancer chemoresistance
Journal: Cell Insight | Authors: Rong Luo | Species: human | Application: WB - Regulation of CHK1 inhibitor resistance by a c-Rel and USP1 dependent pathway
Journal: Biochem J | Authors: Jill E Hunter | Species: mouse | Application: WB
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