FcZero-rAb® CoraLite® Plus 594 Anti-Human B7-H3/CD276 Rabbit Recombinant Antibody CL594-FcA98017 proteintech
$210.00
In stock
SKU
CL594-FcA98017
| Catalog Number | CL594-FcA98017 |
| Synonyms | CD276, 4Ig-B7-H3, B7 H3, B7 homolog 3, B7H3 |
| Host | Rabbit |
| Reactivity | human |
| Form | Liquid |
| Formulation | PBS, Azide, BSA |
| Applications | FC |
| Host / Isotype | Rabbit / IgG |
| Tested Applications — Positive FC detected in | Human immature monocyte-derived dendritic cells |
| Positive FC detected in | Human immature monocyte-derived dendritic cells |
| Flow Cytometry (FC) | FC : 5 ul per 10^6 cells in a 100 µl suspension |
| Tested Reactivity | human |
| Class | Recombinant |
| Type | Antibody |
| Immunogen | CatNo: Eg0075 Product name: Recombinant Human B7-H3/CD276 protein (Myc Tag, His Tag) Source: mammalian cells -derived, pHZ-KIsec Tag: Myc & 6*His Domain: 29-245 aa of NM_001024736 Sequence: LEVQVPEDPVVALVGTDATLCCSFSPEPGFSLAQLNLIWQLTDTKQLVHSFAEGQDQGSAYANRTALFPDLLAQGNASLRLQRVRVADEGSFTCFVSIRDFGSAAVSLQVAAPYSKPSMTLEPNKDLRPGDTVTITCSSYRGYPEAEVFWQDGQGVPLTGNVTTSQMANEQGLFDVHSVLRVVLGANGTYSCLVRNPVLQQDAHGSVTITGQPMTFP Predict reactive species |
| Full Name | CD276 molecule |
| Calculated Molecular Weight | 57 kDa |
| GenBank Accession Number | NM_001024736 |
| Gene Symbol | CD276 |
| Gene ID (NCBI) | 80381 |
| RRID | AB_3748493 |
| Conjugate | CoraLite® Plus 594 Fluorescent Dye |
| Excitation/Emission Maxima Wavelengths | 588 nm / 604 nm |
| Excitation Laser | Yellow-Green Laser (561 nm) |
| Purification Method | Protein A purification |
| UNIPROT ID | Q5ZPR3 |
| Storage Buffer | PBS with 0.09% sodium azide and 0.5% BSA, pH 7.3. |
| Storage Conditions | Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment. |
| FC protocol for CL Plus 594 B7-H3/CD276 antibody CL594-FcA98017 | Download protocol |
| Citations | - |
| Isotype | IgG |
| Clonality | Recombinant |
| Clone Number | 230305A10 |
| Conjugation | CoraLite® Plus 594 |
B7-H3 (CD276) is a type I transmembrane protein expressed on many tissues and cell types. B7-H3 is a 100-kDa glycoprotein that belongs to the B7 immunoregulatory family and participates in the regulation of T-cell-mediated immune response probably by functioning as both a T cell costimulator and coinhibitor (PMID: 25567370; 20696859). Overexpressed on a wide range of human solid cancers, B7-H3 has been implicated in cancer progression and metastasis and becomes an attractive target for cancer immunotherapy (PMID: 27208063). Protocols Product Specific Protocols FC protocol for CL Plus 594 B7-H3/CD276 antibody CL594-FcA98017 Download protocol Standard Protocols Click here to view our Standard Protocols
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