CD80 Polyclonal antibody 14292-1-AP proteintech
$149.00
In stock
SKU
14292-1-AP
| Catalog Number | 14292-1-AP |
| Synonyms | Activation B7 1 antigen, Activation B7-1 antigen, B7, B7 1, B7-1 |
| Host | Rabbit |
| Reactivity | human, mouse and More (1) |
| Reactivity | human, mouse, rat |
| Form | Liquid |
| Formulation | PBS, Azide, Glycerol |
| Applications | WB, ELISA |
| Host / Isotype | Rabbit / IgG |
| Tested Applications — Positive WB detected in | RAW 264.7 cells, human peripheral blood leukocyte, Daudi cells, Raji cells, Ramos cells, J774A.1 cells |
| Recommended Dilutions — Western Blot (WB) | WB : 1:300-1:8000 |
| Positive WB detected in | RAW 264.7 cells, human peripheral blood leukocyte, Daudi cells, Raji cells, Ramos cells, J774A.1 cells |
| Western Blot (WB) | WB : 1:300-1:8000 |
| Tested Reactivity | human, mouse |
| Cited Reactivity | human, mouse, rat |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | CatNo: Ag5615 Product name: Recombinant human B7-1 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 36-228 aa of BC042665 Sequence: IHVTKEVKEVATLSCGHNVSVEELAQTRIYWQKEKKMVLTMMSGDMNIWPEYKNRTIFDITNNLSIVILALRPSDEGTYECVVLKYEKDAFKREHLAEVTLSVKADFPTPSISDFEIPTSNIRRIICSTSGGFPEPHLSWLENGEELNAINTTVSQDPETELYAVSSKLDFNMTTNHSFMCLIKYGHLRVNQT Predict reactive species |
| Full Name | CD80 molecule |
| Calculated Molecular Weight | 33 kDa |
| Observed Molecular Weight | 60 kDa |
| GenBank Accession Number | BC042665 |
| Gene Symbol | CD80 |
| Gene ID (NCBI) | 941 |
| RRID | AB_10640809 |
| Conjugate | Unconjugated |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | P33681 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA. |
| WB protocol for CD80 antibody 14292-1-AP | Download protocol |
| mouse | J Nanobiotechnology Continuous ZnO nanoparticle exposure induces melanoma-like skin lesions in epidermal barrier dysfunction model mice through anti-apoptotic effects mediated by the oxidative stress-activated NF-κB pathway. Authors - Ping Wang View Article |
| Citations | 46 |
| Dilutions | WB : 1:300-1:8000 |
| Isotype | IgG |
| Clonality | Polyclonal |
| Clone Number | - |
| Conjugation | Unconjugated |
CD80 (also known as B7-1) is a type I membrane protein that is a member of the immunoglobulin superfamily, with an extracellular immunoglobulin constant-like domain and a variable-like domain required for receptor binding. It is expressed on antigen-presenting cells (APCs), including B cells, dendritic cells, monocytes, and macrophages. CD80 is the receptor for the proteins CD28 and CTLA-4 found on the surface of T-cells. It is involved in the costimulatory signal essential for T-lymphocyte activation. T-cell proliferation and cytokine production is induced by the binding of CD28, binding to CTLA-4 has opposite effects and inhibits T-cell activation. CD80 also acts as a cellular attachment receptor for adenovirus subgroup B. (PMID: 7545666; 12015893; 16920215) Protocols Product Specific Protocols WB protocol for CD80 antibody 14292-1-AP Download protocol Standard Protocols Click here to view our Standard Protocols
Publications
- Antigen Self-Presented Personalized Nanovaccines Boost the Immunotherapy of Highly Invasive and Metastatic Tumors
Journal: ACS Nano | Authors: Tingting Wang | Species: mouse | Application: WB - Fe(III)-Chelated Polydopamine Nanoparticles for Synergistic Tumor Therapies of Enhanced Photothermal Ablation and Antitumor Immune Activation.
Journal: ACS Appl Mater Interfaces | Authors: Na Xu | Species: mouse - Light-controlled oxygen production and collection for sustainable photodynamic therapy in tumor hypoxia.
Journal: Biomaterials | Authors: Haoran Wang | Species: mouse - Photosynthetic microorganisms coupled photodynamic therapy for enhanced antitumor immune effect.
Journal: Bioact Mater | Authors: Haoran Wang | Species: mouse - Self-Assembly Catalase Nanocomplex Conveyed by Bacterial Vesicles for Oxygenated Photodynamic Therapy and Tumor Immunotherapy.
Journal: Int J Nanomedicine | Authors: Jiayu Zhang | Species: mouse - Continuous ZnO nanoparticle exposure induces melanoma-like skin lesions in epidermal barrier dysfunction model mice through anti-apoptotic effects mediated by the oxidative stress-activated NF-κB pathway.
Journal: J Nanobiotechnology | Authors: Ping Wang | Species: mouse - Pro-efferocytic macrophage membrane biomimetic nanoparticles for the synergistic treatment of atherosclerosis via competition effect
Journal: J Nanobiotechnology | Authors: Xuan Sha | Species: mouse - Light-controlled oxygen production and collection for sustainable photodynamic therapy in tumor hypoxia.
Journal: Biomaterials | Authors: Haoran Wang | Species: mouse - Aggregation-Induced Emission-Active Photosensitizer-Mediated Photodynamic Therapy for Anti-Psoriasis
Journal: Research (Wash D C) | Authors: Ping Zhu | Species: human - Non-cytotoxic nanoparticles re-educating macrophages achieving both innate and adaptive immune responses for tumor therapy
Journal: Asian J Pharm Sci | Authors: Shengmei Wang | Species: mouse | Application: WB - Bioorthogonal conjugation and responsive nanocoating of probiotics for inflammatory bowel disease
Journal: J Control Release | Authors: Pandi Peng | Species: mouse - Thermal/ultrasound-triggered release of liposomes loaded with Ganoderma applanatum polysaccharide from microbubbles for enhanced tumour ablation
Journal: J Control Release | Authors: Jiani Yuan | Species: mouse - Spatiotemporal Immunomodulation of Macrophages via NLRP3/IL-1β Pathway by Core-Shell Microneedles to Promote Healing of Biofilm-Infected Diabetic Ulcers
Journal: Small | Authors: Yushan Yang | Species: mouse - Radioimmunotherapy Targeting B7-H3 in situ glioma models enhanced antitumor efficacy by Reconstructing the tumor microenvironment
Journal: Int J Biol Sci | Authors: Meng Zheng | Species: mouse - M1 macrophages induce PD-L1hi cell-led collective invasion in HPV-positive head and neck squamous cell carcinoma via TNF-α/CDK4/UPS14
Journal: J Immunother Cancer | Authors: Jiashun Wu | Species: human - Immunotherapy landscape analyses of necroptosis characteristics for breast cancer patients.
Journal: J Transl Med | Authors: Honghao Yu | Species: human - Self-Assembly Catalase Nanocomplex Conveyed by Bacterial Vesicles for Oxygenated Photodynamic Therapy and Tumor Immunotherapy.
Journal: Int J Nanomedicine | Authors: Jiayu Zhang | Species: mouse - Sonosensitizer nanoplatform-mediated sonodynamic therapy induced immunogenic cell death and tumor immune microenvironment variation.
Journal: Drug Deliv | Authors: Jing Zheng | Species: mouse - Topical transdermal administration of lenalidomide nanosuspensions-based hydrogels against melanoma: In vitro and in vivo studies
Journal: Int J Pharm X | Authors: Mengdi Zhang | Species: mouse - Fe(III)-Chelated Polydopamine Nanoparticles for Synergistic Tumor Therapies of Enhanced Photothermal Ablation and Antitumor Immune Activation.
Journal: ACS Appl Mater Interfaces | Authors: Na Xu | Species: mouse - Enhanced Immunotherapy Based on Combining the Pro-phagocytosis and Anti-phagocytosis Checkpoint Blockade for Tumor Eradication
Journal: J Med Chem | Authors: Wen Song | Species: mouse - Comprehensive multiomics analysis identifies PYCARD as a key pyroptosis-related gene in osteoarthritis synovial macrophages
Journal: Front Immunol | Authors: Zihao Yao | Species: human | Application: WB - Differential immune responses of C57BL/6 mice to infection by Salmonella enterica serovar Typhimurium strain SL1344, CVCC541 and CMCC50115.
Journal: Virulence | Authors: Shao Wei | Species: mouse | Application: WB - In situ piezoelectricity induces M2 polarization of macrophages to regulate Schwann cells for alleviating neuropathic pain of CCI rats
Journal: Biomater Adv | Authors: Guihua Wei | Species: rat - Indoleamine 2,3-dioxygenase 1 mediated macrophage oxidative phosphorylation impairment drives pro-inflammatory M1 polarization aggravates acetaminophen-induced acute liver injury.
Journal: Ecotoxicol Environ Saf | Authors: Shanshan Kuang | Species: mouse | Application: WB - Electroacupuncture Improves Microglial Polarization Induced-Inflammation by Regulating the TGF-β/Smad-3 Signaling Pathway in Ischemic Stroke Mice
Journal: CNS Neurosci Ther | Authors: Guoqiang Yang - A nanotherapeutic system for gastric cancer suppression by synergistic chemotherapy and immunotherapy based on iPSCs and DCs exosomes
Journal: Cancer Immunol Immunother | Authors: Yezhou Li | Species: mouse - FBP1/HIF-1α Axis mediates macrophage metabolic reprogramming and serves as diagnostic biomarkers in atherosclerosis.
Journal: Int Immunopharmacol | Authors: Min Li | Species: mouse | Application: WB - Interleukin-1β polarization in M1 macrophage mediates myocardial fibrosis in diabetes
Journal: Int Immunopharmacol | Authors: Wenli Guo | Species: mouse - Knockdown of HMGB1 inhibits the crosstalk between oral squamous cell carcinoma cells and tumor-associated macrophages
Journal: Int Immunopharmacol | Authors: Jinlin Wen | Species: human - Neuron-Derived Exosomes Promote the Recovery of Spinal Cord Injury by Modulating Nerve Cells in the Cellular Microenvironment of the Lesion Area
Journal: Mol Neurobiol | Authors: Yi Xu | Species: mouse | Application: WB - A Quinoxaline Derivative as a New Therapeutic Agent for Sepsis through Suppression of TLR4 Signaling Pathways
Journal: Inflammation | Authors: Hamza Hanieh | Species: mouse | Application: WB - MAGL regulates synovial macrophage polarization vis inhibition of mitophagy in osteoarthritic pain
Journal: Mol Med Rep | Authors: Chengyong Gu | Species: mouse - The apparent interferon resistance of transmitted HIV-1 is possibly a consequence of enhanced replicative fitness
Journal: PLoS Pathog | Authors: Elena Sugrue | Species: human | Application: WB - Tumor-secreted GRP78 induces M2 polarization of macrophages by promoting lipid catabolism
Journal: Cell Signal | Authors: Jinmiao Tian | Species: human | Application: WB - Pretreated MSCs with IronQ Transplantation Attenuate Microglia Neuroinflammation via the cGAS-STING Signaling Pathway
Journal: J Inflamm Res | Authors: Guoqiang Yang | Species: mouse | Application: WB - Implications of LAG3 and CTLA4 immune checkpoints beyond PD-1/PD-L1 as a potential target in determining the prognosis of uveal melanoma patients
Journal: Br J Ophthalmol | Authors: Seema Kashyap | Species: human | Application: WB - Synergistic immunomodulatory effects of naringenin and photothermal therapy in triple-negative breast cancer.
Journal: iScience | Authors: Chunyu Lei | Species: mouse | Application: WB,ELISA - AMPK upregulates SOCS1 to promote TFEB nuclear transfer, enhances autophagy, inhibits macrophage M1 polarization and relieves acute lung injury.
Journal: Mol Immunol | Authors: Wensha Nie | Species: mouse | Application: WB - USP18 improves mitochondrial homeostasis by stabilizing PKM2 and promoting M2 polarization in macrophages to relieve acute lung injury.
Journal: Pathol Res Pract | Authors: Wensha Nie - lncRNA DCST1-AS1 Facilitates Oral Squamous Cell Carcinoma by Promoting M2 Macrophage Polarization through Activating NF-κB Signaling.
Journal: J Immunol Res | Authors: Yilong Ai | Species: human - MK8617 inhibits M1 macrophage polarization and inflammation via the HIF-1α/GYS1/UDPG/P2Y14 pathway
Journal: PeerJ | Authors: Lingling Qian | Species: mouse | Application: WB - Tumor-associated macrophages derived exosomal circPLK1 promotes resistance to EGFR inhibitor osimertinib in non-small cell lung cancer.
Journal: Discov Oncol | Authors: Chuankui Li | Species: human - GAD1-mediated GABA elicits aggressive characteristics of human oral cancer cells
Journal: Biochem Biophys Res Commun | Authors: Zhichao Dou | Species: human - PTBP1-TRAF6 Axis Aggravates Chronic Obstructive Pulmonary Disease by Promoting M1 Macrophage Polarization and Impairing Clearance of Neutrophil Extracellular Traps.
Journal: Immunol Invest | Authors: Mingming Zhao | Species: mouse | Application: WB - Vitamin D3 alleviates intestinal injury in necrotizing enterocolitis and lipopolysaccharide-induced inflammatory response in dendritic cells in rats
Journal: Turk J Med Sci | Authors: Bo Ke | Species: rat,mouse - Bio-hybrid Nanostructures Orchestrate Photodynamic Remodeling of the Fusobacterium nucleatum-Associated Colorectal Tumor Niche.
Journal: Adv Mater | Authors: Maliang Tao | Species: mouse - IRF2 exacerbates diabetic neuropathic pain by promoting high glucose-induced M1 polarization through IL-6/STAT3.
Journal: Genes Genomics | Authors: Yuewei Liang
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