BIM/BCL2L11 Recombinant monoclonal antibody 81976-3-RR proteintech
$149.00
In stock
SKU
81976-3-RR
| Catalog Number | 81976-3-RR |
| Synonyms | BCL2L11, BAM, Bcl2-interacting mediator of cell death, Bcl2-L-11, BCL2L11, BIM |
| Host | Rabbit |
| Reactivity | human, mouse |
| Form | Liquid |
| Formulation | PBS, Azide, Glycerol |
| Applications | WB, ELISA |
| Host / Isotype | Rabbit / IgG |
| Tested Applications — Positive WB detected in | PC-12 cells, A20 cells, mouse thymus tissue |
| Recommended Dilutions — Western Blot (WB) | WB : 1:5000-1:50000 |
| Positive WB detected in | PC-12 cells, A20 cells, mouse thymus tissue |
| Western Blot (WB) | WB : 1:5000-1:50000 |
| Tested Reactivity | human, mouse |
| Class | Recombinant |
| Type | Antibody |
| Immunogen | CatNo: Ag11875 Product name: Recombinant human BIM, BCL2L11 protein Source: e coli. -derived, PET28a Tag: 6*His Domain: 1-198 aa of BC033694 Sequence: MAKQPSDVSSECDREGRQLQPAERPPQLRPGAPTSLQTEPQGNPEGNHGGEGDSCPHGSPQGPLAPPASPGPFATRSPLFIFMRRSSLLSRSSSGYFSFDTDRSPAPMSCDKSTQTPSPPCQAFNHYLSAMASMRQAEPADMRPEIWIAQELRRIGDEFNAYYARRVFLNNYQAAEDHPRMVILRLLRYIVRLVWRMH Predict reactive species |
| Full Name | BCL2-like 11 (apoptosis facilitator) |
| Calculated Molecular Weight | 198 aa, 22 kDa |
| Observed Molecular Weight | 16 kDa, 23 kDa |
| GenBank Accession Number | BC033694 |
| Gene Symbol | Bim |
| Gene ID (NCBI) | 10018 |
| RRID | AB_3743397 |
| Conjugate | Unconjugated |
| Purification Method | Protein A purification |
| UNIPROT ID | O43521 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA. |
| WB protocol for BIM/BCL2L11 antibody 81976-3-RR | Download protocol |
| Citations | - |
| Dilutions | WB : 1:5000-1:50000 |
| Isotype | IgG |
| Clonality | Recombinant |
| Clone Number | 252250A2 |
| Conjugation | Unconjugated |
BIM (BCL2L11) is a central BH3-only apoptosis activator that antagonizes anti-apoptotic BCL-2 proteins and directly triggers BAX/BAK-mediated mitochondrial permeabilization. Induced by cellular stress and cytokine withdrawal, BIM governs developmental cell death, immune tolerance, and tumor suppression. Alterations in BIM expression or splicing-particularly the deletion polymorphism affecting its BH3-only activity-underlie cancer therapy resistance, autoimmune disorders, and neuronal apoptosis. Protocols Product Specific Protocols WB protocol for BIM/BCL2L11 antibody 81976-3-RR Download protocol Standard Protocols Click here to view our Standard Protocols
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