CoraLite® Plus 488-conjugated BCL2L1 Monoclonal antibody CL488-66020 proteintech
$479.00
In stock
SKU
CL488-66020
| Catalog Number | CL488-66020 |
| Synonyms | Bcl-xL, 4C12A6, Apoptosis regulator Bcl X, Apoptosis regulator Bcl-X, Bcl2-L-1 |
| Host | Mouse |
| Reactivity | human, canine |
| Form | Liquid |
| Formulation | PBS, Proclin300, BSA, Glycerol |
| Applications | IF/ICC, FC (Intra) |
| Host / Isotype | Mouse / IgG2b |
| Tested Applications — Positive IF/ICC detected in | HeLa cells, MDCK cells |
| Tested Applications — Positive FC (Intra) detected in | Jurkat cells |
| Recommended Dilutions — Immunofluorescence (IF)/ICC | IF/ICC : 1:50-1:500 |
| Recommended Dilutions — Flow Cytometry (FC) (INTRA) | FC (INTRA) : 0.40 ug per 10^6 cells in a 100 µl suspension |
| Positive IF/ICC detected in | HeLa cells, MDCK cells |
| Positive FC (Intra) detected in | Jurkat cells |
| Immunofluorescence (IF)/ICC | IF/ICC : 1:50-1:500 |
| Flow Cytometry (FC) (INTRA) | FC (INTRA) : 0.40 ug per 10^6 cells in a 100 µl suspension |
| Tested Reactivity | human, canine |
| Class | Monoclonal |
| Type | Antibody |
| Immunogen | CatNo: Ag18037 Product name: Recombinant human Bcl-xL protein Source: e coli. -derived, PET28a Tag: 6*His Domain: 1-233 aa of BC019307 Sequence: MSQSNRELVVDFLSYKLSQKGYSWSQFSDVEENRTEAPEGTESEMETPSAINGNPSWHLADSPAVNGATGHSSSLDAREVIPMAAVKQALREAGDEFELRYRRAFSDLTSQLHITPGTAYQSFEQVVNELFRDGVNWGRIVAFFSFGGALCVESVDKEMQVLVSRIAAWMATYLNDHLEPWIQENGGWDTFVELYGNNAAAESRKGQERFNRWFLTGMTVAGVVLLGSLFSRK Predict reactive species |
| Full Name | BCL2-like 1 |
| Calculated Molecular Weight | 26 kDa |
| GenBank Accession Number | BC019307 |
| Gene Symbol | BCL2L1 |
| Gene ID (NCBI) | 598 |
| RRID | AB_2883229 |
| Conjugate | CoraLite® Plus 488 Fluorescent Dye |
| Excitation/Emission Maxima Wavelengths | 493 nm / 522 nm |
| Excitation Laser | Blue laser (488 nm) |
| Purification Method | Protein A purification |
| UNIPROT ID | Q07817 |
| Storage Buffer | PBS with 50% glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3. |
| Storage Conditions | Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. |
| FC protocol for CL Plus 488 BCL2L1 antibody CL488-66020 | Download protocol |
| IF protocol for CL Plus 488 BCL2L1 antibody CL488-66020 | Download protocol |
| Citations | - |
| Dilutions | IF/ICC : 1:50-1:500 FC (INTRA) : 0.40 ug per 10^6 cells in a 100 µl suspension |
| Isotype | IgG2b |
| Clonality | Monoclonal |
| Clone Number | 4C12A6 |
| Conjugation | CoraLite® Plus 488 |
BCL2L1 is a member of the BCL-2 protein family. BCL2L1 is expressed as three isoforms, Bcl-X(L),Bcl-X(s) and Bcl-X(beta), and is located at the outer mitochondrial membrane. The Bcl-XL isoform is a 233 amino acid protein, acting as an apoptotic inhibitor. Bcl-XL can forms heterodimers with BAX, BAK or BCL2, and the heterodimerization with BAX does not seem to be required for anti-apoptotic activity. The Bcl-XS isoform is a shorter variant that is 178 amino acids in length and lacks a 63 amino acid region (amino acids 126-188), acting as an apoptotic activator. Protocols Product Specific Protocols FC protocol for CL Plus 488 BCL2L1 antibody CL488-66020 Download protocol IF protocol for CL Plus 488 BCL2L1 antibody CL488-66020 Download protocol Standard Protocols Click here to view our Standard Protocols
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