Human/Mouse/Rat TDO2 ELISA Kit KE00932 proteintech
$299.00
In stock
SKU
KE00932
| Product name | Human/Mouse/Rat TDO2 ELISA Kit |
| Synonyms | EC:1.13.11.11, TDO, TO, TPH2, TRPO |
| Reactivity | Human/Mouse/Rat |
| Host / Isotype | United States |
| Tests | 1 X 96 well plate |
| Sample type | Tissue lysate |
| Assay type | Sandwich |
| Sensitivity | 0.22 ng/mL |
| Range | 1.56-100 ng/mL |
| Tested applications | Sandwich ELISA |
| Gene ID (NCBI) | 6999 |
| Sample Type | Average Range |
| Tissue lysate | 86% 78%-104% |
| Sample | n mean ( ng/mL ) SD CV% |
| 1 | 16 50.02 5.55 11.09 |
| 2 | 16 10.37 0.65 6.23 |
| 3 | 16 2.38 0.17 7.33 |
| Storage Instructions | All the reagents are stored at 2-8℃ for 6 months or -20℃ for 12 months. Refer to the protocol for further storage instructions. |
TDO2 (tryptophan 2,3-dioxygenase) is a heme-containing intracellular enzyme that is primarily localized in the cytoplasm. It catalyzes the first step in tryptophan metabolism, converting tryptophan to kynurenine. This process plays a key role in immune regulation by suppressing T cell activity to maintain immune homeostasis. TDO2 is highly expressed in various cancers, such as glioma, breast cancer, and colorectal cancer. Its high expression is associated with tumor progression and an immunosuppressive microenvironment, making it a potential target for cancer immunotherapy. In addition, TDO2 is also involved in cardiovascular diseases and metabolic regulation, holding significant biological and clinical research value. Properties Storage Instructions All the reagents are stored at 2-8℃ for 6 months or -20℃ for 12 months. Refer to the protocol for further storage instructions. Synonyms EC:1.13.11.11, TDO, TO, TPH2, TRPO FAQ 1、I have limited sample diluent. How should I handle samples requiring high dilution factors? Answer: We recommend performing a serial dilution. For example, if human serum requires a 1,000,000-fold dilution, you can use a three-step 100× dilution method as follows: Step 1: Take 2 uL of human serum and add it to 198 uL of sample diluent, mix thoroughly to obtain a 100-fold diluted sample. Step 2: Take 2 uL of the 100-fold diluted sample and add it to 198 uL of sample diluent, mix thoroughly to obtain a 10,000-fold diluted sample. Step 3: Take 2 uL of the 10,000-fold diluted sample and add it to 198 uL of sample diluent, mix thoroughly to obtain a 1,000,000-fold diluted sample. If further dilution is required, additional serial steps can be used. We do not recommend using any other solutions or water for dilution, except for the sample diluent we suggest. If your sample diluent is still insufficient, please contact our customer service for more sample diluent.
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