Mouse SIGNR1/CD209b ELISA Kit KE10183 proteintech
$299.00
In stock
SKU
KE10183
| Product name | Mouse SIGNR1/CD209b ELISA Kit |
| Synonyms | CD209, CD209 antigen-like protein B, Cd209b, DC-SIGNR1, DC-SIGN-related protein 1 |
| Reactivity | Mouse |
| Host / Isotype | United States |
| Tests | 1 X 96 well plate |
| Sample type | Tissue lysate |
| Assay type | Sandwich |
| Sensitivity | 2.5 pg/mL |
| Range | 125-8000 pg/mL |
| Tested applications | Sandwich ELISA |
| Gene ID (NCBI) | 69165 |
| Sample Type | Average Range |
| Tissue lysate | 86% 77%-94% |
| Sample | n mean ( pg/mL ) SD CV% |
| 1 | 16 3,814.4 322.9 8.5 |
| 2 | 16 932.2 65.7 7.0 |
| 3 | 16 469.4 41.8 8.9 |
| Storage Instructions | All the reagents are stored at 2-8℃ for 6 months or -20℃ for 12 months. Refer to the protocol for further storage instructions. |
SIGNR1, also known as CD209b, is a type II transmembrane C-type lectin that plays a crucial role in immune recognition and phagocytosis. It is involved in the uptake of dextran polysaccharides, including the capsular polysaccharide of Streptococcus pneumoniae. SIGNR1 is physically associated with TLR4/MD2, which is suggested to play a role in the recognition of LPS. Additionally, SIGNR1 has been shown to bind directly to the complement C1 subcomponent, C1q, to assemble a non-conventional C3 convertase. In the context of cancer, SIGNR1 mediates IL-4-induced macrophage polarization, facilitating immune evasion in lung cancer. Properties Storage Instructions All the reagents are stored at 2-8℃ for 6 months or -20℃ for 12 months. Refer to the protocol for further storage instructions. Synonyms CD209, CD209 antigen-like protein B, Cd209b, DC-SIGNR1, DC-SIGN-related protein 1 FAQ 1、I have limited sample diluent. How should I handle samples requiring high dilution factors? Answer: We recommend performing a serial dilution. For example, if human serum requires a 1,000,000-fold dilution, you can use a three-step 100× dilution method as follows: Step 1: Take 2 uL of human serum and add it to 198 uL of sample diluent, mix thoroughly to obtain a 100-fold diluted sample. Step 2: Take 2 uL of the 100-fold diluted sample and add it to 198 uL of sample diluent, mix thoroughly to obtain a 10,000-fold diluted sample. Step 3: Take 2 uL of the 10,000-fold diluted sample and add it to 198 uL of sample diluent, mix thoroughly to obtain a 1,000,000-fold diluted sample. If further dilution is required, additional serial steps can be used. We do not recommend using any other solutions or water for dilution, except for the sample diluent we suggest. If your sample diluent is still insufficient, please contact our customer service for more sample diluent.
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