Human CCL3 ELISA Kit KE00092 proteintech
$299.00
In stock
SKU
KE00092
| Product name | Human CCL3 ELISA Kit |
| Synonyms | C C motif chemokine 3, CCL3, chemokine (C C motif) ligand 3, G0S19 1, LD78 alpha(4 69), LD78ALPHA, MIP 1 alpha, MIP1A, PAT 464.1, SCYA3, SIS beta, Small inducible cytokine A3 |
| Reactivity | Human |
| Host / Isotype | United States |
| Tests | 1 X 96 well plate |
| Sample type | Serum, Plasma, Cell culture supernatants |
| Assay type | Sandwich |
| Sensitivity | 0.06 pg/mL |
| Range | 1.95 - 125 pg/mL |
| Tested applications | Sandwich ELISA |
| Gene ID (NCBI) | 6348 |
| Sample Type | Average Range |
| Human plasma | 96% 84%-106% |
| Cell culture supernatants | 97% 86%-107% |
| Sample | n mean ( pg/mL ) SD CV% |
| 1 | 24 119.4 5.9 5.0 |
| 2 | 24 27.8 1.3 4.6 |
| 3 | 24 2.4 0.1 4.3 |
| Storage Instructions | All the reagents are stored at 2-8℃ for 6 months or -20℃ for 12 months. Refer to the protocol for further storage instructions. |
| human | Serum, Plasma, Cell culture supernatants Cancer Immunol Immunother Longitudinal plasma proteomic analysis identifies biomarkers and combinational targets for anti-PD1-resistant cancer patients. Authors - Qiaoyun Tan View Article |
Chemokine (C-C motif) ligand 3 (CCL3), also known as MIP-1α, belongs to the family of chemokines. CCL3 has been found in the central nervous system and its cognate receptors, CCR1 and CCR5, have been reported to be expressed by astrocytes, microglia and neurons. CCL3 and its receptors, CCR1 and CCR5, also contribute to the development of bone disease in multiple myeloma by supporting tumor growth and regulating osteoclast differentiation. CCL3 is also associated with the regulation of cell growth, angiogenesis, and metastasis of different tumors such as melanoma, renal cell carcinoma, and colorectal cancer. Moreover, CCL3 enhances cell migration and metastasis by up-regulating matrix metalloproteinase-2 (MMP)-2 expression in chondrosarcoma cells. Properties Storage Instructions All the reagents are stored at 2-8℃ for 6 months or -20℃ for 12 months. Refer to the protocol for further storage instructions. Synonyms C C motif chemokine 3, CCL3, chemokine (C C motif) ligand 3, G0S19 1, LD78 alpha(4 69), LD78ALPHA, MIP 1 alpha, MIP1A, PAT 464.1, SCYA3, SIS beta, Small inducible cytokine A3 FAQ 1、I have limited sample diluent. How should I handle samples requiring high dilution factors? Answer: We recommend performing a serial dilution. For example, if human serum requires a 1,000,000-fold dilution, you can use a three-step 100× dilution method as follows: Step 1: Take 2 uL of human serum and add it to 198 uL of sample diluent, mix thoroughly to obtain a 100-fold diluted sample. Step 2: Take 2 uL of the 100-fold diluted sample and add it to 198 uL of sample diluent, mix thoroughly to obtain a 10,000-fold diluted sample. Step 3: Take 2 uL of the 10,000-fold diluted sample and add it to 198 uL of sample diluent, mix thoroughly to obtain a 1,000,000-fold diluted sample. If further dilution is required, additional serial steps can be used. We do not recommend using any other solutions or water for dilution, except for the sample diluent we suggest. If your sample diluent is still insufficient, please contact our customer service for more sample diluent.
Publications
- S100A5 Attenuates Efficiency of Anti-PD-L1/PD-1 Immunotherapy by Inhibiting CD8+ T Cell-Mediated Anti-Cancer Immunity in Bladder Carcinoma
Journal: Adv Sci (Weinh) | Authors: Huihuang Li | Species: human | Application: cell culture supernatants - Macrophagic Extracellular Vesicle CXCL2 Recruits and Activates the Neutrophil CXCR2/PKC/NOX4 Axis in Sepsis.
Journal: J Immunol | Authors: Guozhen Wang | Species: human | Application: serum - Plasma CCL3 predicts adverse heart failure outcomes in patients with arrhythmogenic cardiomyopathy
Journal: BMC Med | Authors: Hao Cui | Species: human | Application: plasma - Bufei Yishen Formula Inhibits the Cell Senescence in COPD by Up-Regulating the ZNF263 and Klotho Expression
Journal: Int J Chron Obstruct Pulmon Dis | Authors: Weimin Wang | Species: human | Application: cell culture supernatants - SRGN promotes macrophage recruitment through CCL3 in osteoarthritis
Journal: Connect Tissue Res | Authors: Yi Zhang | Species: human | Application: cell culture supernatants - Longitudinal plasma proteomic analysis identifies biomarkers and combinational targets for anti-PD1-resistant cancer patients.
Journal: Cancer Immunol Immunother | Authors: Qiaoyun Tan | Species: human | Application: Serum, Plasma, Cell culture supernatants - Macrophagic Extracellular Vesicle CXCL2 Recruits and Activates the Neutrophil CXCR2/PKC/NOX4 Axis in Sepsis.
Journal: J Immunol | Authors: Guozhen Wang | Species: human - SRGN promotes macrophage recruitment through CCL3 in osteoarthritis
Journal: Connect Tissue Res | Authors: Yi Zhang | Species: human
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