Human CNR2 ELISA Kit KE01017 proteintech
$299.00
In stock
SKU
KE01017
| Product name | Human CNR2 ELISA Kit |
| Synonyms | Cannabinoid receptor 2, CB 2, CB2, CB-2, CB2A |
| Reactivity | Human |
| Host / Isotype | United States |
| Tests | 1 X 96 well plate |
| Sample type | Cell lysate |
| Assay type | Sandwich |
| Sensitivity | 0.02 ng/mL |
| Range | 0.313-20 ng/mL |
| Tested applications | Sandwich ELISA |
| Gene ID (NCBI) | 1269 |
| Sample Type | Average Range |
| Cell lysate | 115% 101%-123% |
| Sample | n mean ( ng/mL ) SD CV% |
| 1 | 16 10.30 0.46 4.44 |
| 2 | 16 2.71 0.11 4.07 |
| 3 | 16 0.81 0.04 4.47 |
| Storage Instructions | All the reagents are stored at 2-8℃ for 6 months or -20℃ for 12 months. Refer to the protocol for further storage instructions. |
CNR2, also known as Cannabinoid Receptor 2 (CB2), is a G protein-coupled receptor (GPCR) of the endocannabinoid system predominantly expressed in immune tissues such as the spleen and leukocytes. Activated by endogenous cannabinoids like 2-arachidonoylglycerol (2-AG) and anandamide (AEA), CNR2 couples to Gi/o proteins, inhibiting adenylyl cyclase and modulating MAPK and PI3K/AKT signaling. It regulates immune cell migration, cytokine release, and inflammatory responses. In cancer, CNR2 signaling shows dual roles: it can suppress tumor growth and angiogenesis, yet under certain conditions may enhance tumor survival and immune evasion. Owing to its limited expression in the CNS and non-psychoactive profile, CNR2 is a promising therapeutic target for inflammatory diseases, neuropathic pain, and cancer immunotherapy. Properties Storage Instructions All the reagents are stored at 2-8℃ for 6 months or -20℃ for 12 months. Refer to the protocol for further storage instructions. Synonyms Cannabinoid receptor 2, CB 2, CB2, CB-2, CB2A FAQ 1、I have limited sample diluent. How should I handle samples requiring high dilution factors? Answer: We recommend performing a serial dilution. For example, if human serum requires a 1,000,000-fold dilution, you can use a three-step 100× dilution method as follows: Step 1: Take 2 uL of human serum and add it to 198 uL of sample diluent, mix thoroughly to obtain a 100-fold diluted sample. Step 2: Take 2 uL of the 100-fold diluted sample and add it to 198 uL of sample diluent, mix thoroughly to obtain a 10,000-fold diluted sample. Step 3: Take 2 uL of the 10,000-fold diluted sample and add it to 198 uL of sample diluent, mix thoroughly to obtain a 1,000,000-fold diluted sample. If further dilution is required, additional serial steps can be used. We do not recommend using any other solutions or water for dilution, except for the sample diluent we suggest. If your sample diluent is still insufficient, please contact our customer service for more sample diluent.
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