| Product name | Human GBP2 ELISA Kit |
| Synonyms | EC:3.6.5.-, GBP 2, GBP-2, GTP-binding protein 2, Guanine nucleotide-binding protein 2 |
| Reactivity | Human |
| Host / Isotype | United States |
| Tests | 1 X 96 well plate |
| Sample type | Cell lysate |
| Assay type | Sandwich |
| Sensitivity | 3.9 pg/mL |
| Range | 78.1-5000 pg/mL |
| Tested applications | Sandwich ELISA |
| Gene ID (NCBI) | 2634 |
| Sample Type | Average Range |
| Cell lysate | 92% 89%-95% |
| Sample | n mean ( pg/mL ) SD CV% |
| 1 | 16 2,595.6 100.3 3.9 |
| 2 | 16 602.1 17.9 3.0 |
| 3 | 16 307.0 30.6 10.0 |
| Storage Instructions | All the reagents are stored at 2-8℃ for 6 months or -20℃ for 12 months. Refer to the protocol for further storage instructions. |
Guanylate binding protein 2 (GBP2) is a member of the guanine binding protein (GBP) family that can bind to guanine nucleotides (GMP, GDP, and GTP). GBP2 is used as a marker of interferon (IFN) responsiveness, because it is one of the most highly expressed genes after IFN-γ stimulation. GBP2 involved in various immune responses and plays a role in the host defense against pathogens. Additionally, GBP2 has been identified as a prognostic biomarker in certain cancers, including breast cancer and clear cell renal cell carcinoma. GBP2 also participates in the regulation of immune responses through pathways like STAT1 signaling. Properties Storage Instructions All the reagents are stored at 2-8℃ for 6 months or -20℃ for 12 months. Refer to the protocol for further storage instructions. Synonyms EC:3.6.5.-, GBP 2, GBP-2, GTP-binding protein 2, Guanine nucleotide-binding protein 2 FAQ 1、I have limited sample diluent. How should I handle samples requiring high dilution factors? Answer: We recommend performing a serial dilution. For example, if human serum requires a 1,000,000-fold dilution, you can use a three-step 100× dilution method as follows: Step 1: Take 2 uL of human serum and add it to 198 uL of sample diluent, mix thoroughly to obtain a 100-fold diluted sample. Step 2: Take 2 uL of the 100-fold diluted sample and add it to 198 uL of sample diluent, mix thoroughly to obtain a 10,000-fold diluted sample. Step 3: Take 2 uL of the 10,000-fold diluted sample and add it to 198 uL of sample diluent, mix thoroughly to obtain a 1,000,000-fold diluted sample. If further dilution is required, additional serial steps can be used. We do not recommend using any other solutions or water for dilution, except for the sample diluent we suggest. If your sample diluent is still insufficient, please contact our customer service for more sample diluent.