Human IL18BP ELISA Kit KE00454 proteintech
$299.00
In stock
SKU
KE00454
| Product name | Human IL18BP ELISA Kit |
| Synonyms | IL 18BP, IL-18BP, IL18BPa, interleukin 18 binding protein, Interleukin-18-binding protein |
| Reactivity | Human |
| Host / Isotype | United States |
| Tests | 1 X 96 well plate |
| Sample type | Serum, Plasma, Urine |
| Assay type | Sandwich |
| Sensitivity | 0.08 ng/mL |
| Range | 0.234-15 ng/mL |
| Tested applications | Sandwich ELISA |
| Gene ID (NCBI) | 10068 |
| Sample Type | Average Range |
| Human serum | 98% 94%-102% |
| Urine | 99% 91%-109% |
| Sample | n mean ( ng/mL ) SD CV% |
| 1 | 16 7.08 0.19 2.68 |
| 2 | 16 2.05 0.04 2.12 |
| 3 | 16 1.22 0.04 3.27 |
| Storage Instructions | All the reagents are stored at 2-8℃ for 6 months or -20℃ for 12 months. Refer to the protocol for further storage instructions. |
IL-18 Binding Protein (IL18BP) is a soluble protein that acts as a natural antagonist of interleukin-18 (IL-18), a pro-inflammatory cytokine involved in immune responses. It binds to IL-18 with high affinity, preventing IL-18 from interacting with its receptors (IL-18Rα and IL-18Rβ) and thus inhibiting its biological activity. This regulation is crucial for maintaining immune homeostasis and preventing excessive inflammation. IL18BP is a biomarker for disease activity and severity, as well as a therapeutic target in cancer immunotherapy. Properties Storage Instructions All the reagents are stored at 2-8℃ for 6 months or -20℃ for 12 months. Refer to the protocol for further storage instructions. Synonyms IL 18BP, IL-18BP, IL18BPa, interleukin 18 binding protein, Interleukin-18-binding protein FAQ 1、I have limited sample diluent. How should I handle samples requiring high dilution factors? Answer: We recommend performing a serial dilution. For example, if human serum requires a 1,000,000-fold dilution, you can use a three-step 100× dilution method as follows: Step 1: Take 2 uL of human serum and add it to 198 uL of sample diluent, mix thoroughly to obtain a 100-fold diluted sample. Step 2: Take 2 uL of the 100-fold diluted sample and add it to 198 uL of sample diluent, mix thoroughly to obtain a 10,000-fold diluted sample. Step 3: Take 2 uL of the 10,000-fold diluted sample and add it to 198 uL of sample diluent, mix thoroughly to obtain a 1,000,000-fold diluted sample. If further dilution is required, additional serial steps can be used. We do not recommend using any other solutions or water for dilution, except for the sample diluent we suggest. If your sample diluent is still insufficient, please contact our customer service for more sample diluent.
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