Mouse CX3CL1 ELISA Kit KE10141 proteintech
$299.00
In stock
SKU
KE10141
| Product name | Mouse CX3CL1 ELISA Kit |
| Synonyms | Cx3cl1,ABCD 3,CX3C,Cxc3,Scyd1 |
| Reactivity | Mouse |
| Host / Isotype | United States |
| Tests | 1 X 96 well plate |
| Sample type | Serum, Plasma, Tissue lysate |
| Assay type | Sandwich |
| Sensitivity | 29.4 pg/mL |
| Range | 78.1-5000 pg/mL |
| Tested applications | Sandwich ELISA |
| Gene ID (NCBI) | 20312 |
| Sample Type | Average Range |
| Tissue lysate | 102% 97%-109% |
| Mouse serum | 98% 89%-105% |
| Sample | n mean ( pg/mL ) SD CV% |
| 1 | 24 2,451.8 177.1 7.2 |
| 2 | 24 625.0 27.1 4.3 |
| 3 | 24 184.9 15.8 8.6 |
| Storage Instructions | All the reagents are stored at 2-8℃ for 6 months or -20℃ for 12 months. Refer to the protocol for further storage instructions. |
| mouse | Serum, Plasma, Tissue lysate Int Immunopharmacol Macrophage DHX34 as a negative regulator of the CX3CL1-CX3CR1 axis and CD8(+) T-cell infiltration in hepatocellular carcinoma. Authors - Zeyu Li View Article |
Chemokines direct the trafficking of white blood cells in immune surveillance, playing a key role in inflammatory and infectious diseases such as AIDS. CX3CL1, also known as fractalkine (FKN), is a unique, membrane-bound chemokine, with a transmembrane domain and the chemokine domain on top of a long mucinlike stalk. This protein can exist in two forms, a membrane-bound form or a shed soluble form, after extracellular proteolysis at a membrane-proximal dibasic cleavage site. The soluble CX3CL1 has potent chemoattractant activity for T cells and monocytes, and the cell-surface-bound protein, which is induced by primary proinflammatory signals in activated primary endothelial cells, promotes strong adhesion of those leukocytes. Presence of CX3CL1 and its receptor CX3CR1 in lymphocytes and their enhanced cellular expression during inflammatory conditions suggests that the CX3CL1-CX3CR1 duo participates in immune-related inflammatory diseases. Properties Storage Instructions All the reagents are stored at 2-8℃ for 6 months or -20℃ for 12 months. Refer to the protocol for further storage instructions. Synonyms Cx3cl1,ABCD 3,CX3C,Cxc3,Scyd1 FAQ 1、I have limited sample diluent. How should I handle samples requiring high dilution factors? Answer: We recommend performing a serial dilution. For example, if human serum requires a 1,000,000-fold dilution, you can use a three-step 100× dilution method as follows: Step 1: Take 2 uL of human serum and add it to 198 uL of sample diluent, mix thoroughly to obtain a 100-fold diluted sample. Step 2: Take 2 uL of the 100-fold diluted sample and add it to 198 uL of sample diluent, mix thoroughly to obtain a 10,000-fold diluted sample. Step 3: Take 2 uL of the 10,000-fold diluted sample and add it to 198 uL of sample diluent, mix thoroughly to obtain a 1,000,000-fold diluted sample. If further dilution is required, additional serial steps can be used. We do not recommend using any other solutions or water for dilution, except for the sample diluent we suggest. If your sample diluent is still insufficient, please contact our customer service for more sample diluent.
Publications
- Macrophage DHX34 as a negative regulator of the CX3CL1-CX3CR1 axis and CD8(+) T-cell infiltration in hepatocellular carcinoma.
Journal: Int Immunopharmacol | Authors: Zeyu Li | Species: mouse | Application: Serum, Plasma, Tissue lysate
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