Mouse IL-6 ELISA Kit KE10091 proteintech
$299.00
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SKU
KE10091
| Product name | Mouse IL-6 ELISA Kit |
| Synonyms | Il 6, Il6, interleukin 6 |
| Reactivity | Mouse |
| Host / Isotype | United States |
| Tests | 1 X 96 well plate |
| Sample type | Serum, Plasma, Cell culture supernatants |
| Assay type | Sandwich |
| Sensitivity | 4.0 pg/mL |
| Range | 12.5-800 pg/mL |
| Tested applications | Sandwich ELISA |
| Gene ID (NCBI) | 16193 |
| Sample Type | Average Range |
| Mouse serum | 88% 84%-108% |
| Cell culture supernatants | 89% 74%-106% |
| Sample | n mean ( pg/mL ) SD CV% |
| 1 | 24 412.9 12.7 3.1 |
| 2 | 24 99.4 3.3 3.3 |
| 3 | 24 24.8 1.1 4.6 |
| Storage Instructions | All the reagents are stored at 2-8℃ for 6 months or -20℃ for 12 months. Refer to the protocol for further storage instructions. |
| mouse | Serum, Plasma, Cell culture supernatants J Exp Med Tet2 deficiency-induced expansion of monocyte-derived macrophages promotes liver fibrosis. Authors - Jiuxing Feng View Article |
Interleukin-6 (IL-6) is an interleukin that acts as both a pro-inflammatory and anti-inflammatory cytokine. IL-6 protein is secreted by a variety of cell types including T cells and macrophages as phosphorylated and variably glycosylated molecule. IL-6 plays an essential role in the final differentiation of B-cells into Ig-secreting cells involved in lymphocyte and monocyte differentiation. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation. IL-6 is also considered a myokine, a cytokine produced from muscle, and is elevated in response to muscle contraction. IL-6 has been shown to interact with interleukin-6 receptor and glycoprotein 130. Additionally, IL-6 is involved in hematopoiesis, bone metabolism, and cancer progression, and has been defined an essential role in directing transition from innate to acquired immunity. Properties Storage Instructions All the reagents are stored at 2-8℃ for 6 months or -20℃ for 12 months. Refer to the protocol for further storage instructions. Synonyms Il 6, Il6, interleukin 6 FAQ 1、I have limited sample diluent. How should I handle samples requiring high dilution factors? Answer: We recommend performing a serial dilution. For example, if human serum requires a 1,000,000-fold dilution, you can use a three-step 100× dilution method as follows: Step 1: Take 2 uL of human serum and add it to 198 uL of sample diluent, mix thoroughly to obtain a 100-fold diluted sample. Step 2: Take 2 uL of the 100-fold diluted sample and add it to 198 uL of sample diluent, mix thoroughly to obtain a 10,000-fold diluted sample. Step 3: Take 2 uL of the 10,000-fold diluted sample and add it to 198 uL of sample diluent, mix thoroughly to obtain a 1,000,000-fold diluted sample. If further dilution is required, additional serial steps can be used. We do not recommend using any other solutions or water for dilution, except for the sample diluent we suggest. If your sample diluent is still insufficient, please contact our customer service for more sample diluent.
Publications
- The role of forkhead box M1-methionine adenosyltransferase 2 A/2B axis in liver inflammation and fibrosis
Journal: Nat Commun | Authors: Bing Yang | Species: mouse | Application: cell culture supernatants - Hyaluronic acid-coated polypeptide nanogel enhances specific distribution and therapy of tacrolimus in rheumatoid arthritis
Journal: J Nanobiotechnology | Authors: Yuhuan Li | Species: mouse | Application: serum - Amplifying hepatic L-aspartate levels suppresses CCl4-induced liver fibrosis by reversing glucocorticoid receptor β-mediated mitochondrial malfunction
Journal: Pharmacol Res | Authors: Rui Su | Species: mouse | Application: plasma - Mitochondrial SIRT2-mediated CPT2 deacetylation prevents diabetic cardiomyopathy by impeding cardiac fatty acid oxidation
Journal: Int J Biol Sci | Authors: Yaoyao Guo - Adenosine metabolic clearance maintains liver homeostasis by licensing arginine methylation of RIPK1
Journal: J Exp Med | Authors: Ran Liu - Tet2 deficiency-induced expansion of monocyte-derived macrophages promotes liver fibrosis.
Journal: J Exp Med | Authors: Jiuxing Feng | Species: mouse | Application: Serum, Plasma, Cell culture supernatants - Artesunate triggers ferroptosis in ovarian cancer via GP130-mediated IL-6/STAT3/OTUB1/SLC711 axis disruption.
Journal: Phytomedicine | Authors: Dengyun Nie | Species: human | Application: ELISA - Enhanced Antibacterial And Wound Healing Using A Metal-Organic Cluster Inspired by Artificial Photosynthesis
Journal: Adv Healthc Mater | Authors: Long Zhu | Species: mouse - Porcine GWAS identifies ACOT11 as regulator for macrophage IL-1β maturation via IFNGR2 palmitoylation
Journal: Sci China Life Sci | Authors: Meimei Zhang | Species: mouse - Self-crosslinking hyaluronic acid hydrogel as an enteroprotective agent for the treatment of inflammatory bowel disease
Journal: Int J Biol Macromol | Authors: Guangshuai Zhang | Species: mouse - The Indicine X-linked CYBBL237M Mutation Can Suppress Intracellular Infection with Tubercle Bacilli.
Journal: Genomics Proteomics Bioinformatics | Authors: Haoxin Wang | Species: mouse | Application: ELISA - Guben Qingfei decoction attenuates LPS-induced acute lung injury by modulating the TLR4/NF-κB and Keap1/Nrf2 signaling pathways
Journal: J Ethnopharmacol | Authors: Ziyuan Zeng | Species: mouse | Application: ELISA - Role of DNMT3a expression and nuclear translocation under ELAVL1 mediation for dendritic cell function and Th17/Treg balance in COPD
Journal: Transl Res | Authors: Dan Huang | Species: mouse - Isoliquiritigenin alleviates neuropathic pain by reducing microglia inflammation through inhibition of the ERK signaling pathway and decreasing CEBPB transcription expression
Journal: Int Immunopharmacol | Authors: Zikun Wang | Species: mouse - Eicosapentaenoic acid enhances the sensitivity of osteosarcoma to cisplatin by inducing ferroptosis through the DNA-PKcs/AKT/NRF2 pathway and reducing PD-L1 expression to attenuate immune evasion
Journal: Int Immunopharmacol | Authors: Yining Zhang - METTL3 Potentiates Corneal Allograft Rejection via Increased Pro-Inflammatory Cytokine Production and Aerobic Glycolysis.
Journal: Invest Ophthalmol Vis Sci | Authors: Huimin Yu | Species: mouse | Application: ELISA - Discovery of a novel quinoline RIP1 inhibitor and its treatment of acute liver injury in mice
Journal: Bioorg Chem | Authors: Bin Xu | Species: mouse - Potential of Ginger Oil to Prevent 4-(Methylnitrosamino)-1-(3-Pyridyl)-1-Butanone-Induced Lung Cancer Through Gut Microbiota Modulation and Inflammatory Response Inhibition
Journal: Mol Nutr Food Res | Authors: Yan Ding | Species: mouse | Application: ELISA - Potential of Ginger Oil to Prevent 4-(Methylnitrosamino)-1-(3-Pyridyl)-1-Butanone-Induced Lung Cancer Through Gut Microbiota Modulation and Inflammatory Response Inhibition
Journal: Mol Nutr Food Res | Authors: Yan Ding | Species: mouse | Application: ELISA - Tilianin alleviates lipid deposition and fibrosis in mice with nonalcoholic steatohepatitis by activating the PPARα/Nnat axis
Journal: Drug Dev Res | Authors: Fan Ke | Species: mouse - Interpreting the chemical changes and therapeutic effect of Coptidis Rhizoma against ulcerative colitis before and after processing based on mathematical statistics and network pharmacology
Journal: Phytochem Anal | Authors: Chunxia Li | Species: mouse - Cytotoxic and anti-inflammatory constituents from roots of Hypericum beanii and the antitumor potential under the view of cancer-related inflammation
Journal: Fitoterapia | Authors: Wei Ma | Species: mouse - Ultrasound modulates microglial activity and reduces neuroinflammation in a parameter-dependent manner.
Journal: NPJ Acoust | Authors: Sarina Grewal | Species: mouse - Prebiotic raffinose attenuates surgery-induced delirium-like behaviors through gut microbiota-mediated serotonergic signaling in frail senescence-accelerated mice: an experimental study using SAMP10 mice.
Journal: J Anesth | Authors: Noriaki Nishihara
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