| Product name | IHCeasy AFF4 Ready-To-Use IHC Kit |
| Synonyms | AF4/FMR2 family member 4, AF4/FMR2 family, member 4, AF5Q31, AFF4, MCEF, Protein AF 5q31 |
| Reactivity | Human |
| Host / Isotype | United States |
| Sample type | FFPE tissue |
| Assay type | Immunohistochemistry |
| Primary antibody type | Rabbit Polyclonal |
| Secondary antibody type | Polymer-HRP-Goat anti-Rabbit |
| Component | Size Concentration |
| Antigen Retrieval Buffer | 100 mL 50× |
| Washing Buffer | 100 mL ×2 20× |
| Blocking Buffer | 5 mL RTU |
| Primary Antibody | 5 mL RTU |
| Secondary Antibody | 5 mL RTU |
| Chromogen Component A | 0.2 mL RTU |
| Chromogen Component B | 4 mL RTU |
| Signal Enhancer | 5 mL RTU |
| Counter Staining Reagent | 5 mL RTU |
| Mounting Media | 5 mL RTU |
| Datasheet | 1 Copy |
| Manual | 1 Copy |
| Storage Instructions | All the reagents are stored at 2-8°C. The kit is stable for 6 months from the date of receipt. |
Transcriptional controled by RNA polymerase II (Pol II) is a multi-step process requiring the concerted action of multiple factors and contacts with the DNA template for the proper synthesis of nascent RNA. ELL1 was demonstrated to be a Pol II elongation factor capable of enhancing the catalytic rate of transcription elongation by reducing transient pausing by the enzyme. AFF4 was initially identified as a fusion partner of the MLL (mixed-lineage leukemia) gene participated in infant acute lymphoblastic leukemia, and a component of the ELL/p-TEFb elongation complex. AFF4 interacts with positive transcription elongation factor-b while also repressing Tat transactivation of HIV-1. Properties Storage Instructions All the reagents are stored at 2-8°C. The kit is stable for 6 months from the date of receipt. Synonyms AF4/FMR2 family member 4, AF4/FMR2 family, member 4, AF5Q31, AFF4, MCEF, Protein AF 5q31 × Select download options English Czech Danish German Spanish Finnish French Hungarian Italian Lithuanian Dutch Norwegian-Bokmol Polish Portuguese Slovak Swedish Download