IHC easy ® IBA1 Ready-To-Use IHC Kit KHC0056 proteintech
$489.00
In stock
SKU
KHC0056
| Product name | IHCeasy IBA1 Ready-To-Use IHC Kit |
| Synonyms | AIF 1, AIF1, G1, IBA1, IRT 1, Protein G1 |
| Reactivity | Human, Mouse, Rat |
| Host / Isotype | United States |
| Sample type | FFPE tissue |
| Assay type | Immunohistochemistry |
| Primary antibody type | Rabbit Polyclonal |
| Secondary antibody type | Polymer-HRP-Goat anti-Rabbit |
| Component | Size Concentration |
| Antigen Retrieval Buffer | 100 mL 50× |
| Washing Buffer | 100 mL ×2 20× |
| Blocking Buffer | 5 mL RTU |
| Primary Antibody | 5 mL RTU |
| Secondary Antibody | 5 mL RTU |
| Chromogen Component A | 0.2 mL RTU |
| Chromogen Component B | 4 mL RTU |
| Signal Enhancer | 5 mL RTU |
| Counter Staining Reagent | 5 mL RTU |
| Mounting Media | 5 mL RTU |
| Datasheet | 1 Copy |
| Manual | 1 Copy |
| Storage Instructions | All the reagents are stored at 2-8°C. The kit is stable for 6 months from the date of receipt. |
IBA1, or AIF1 daintain/AIF-1, is a 143 amino acid cytoplasmic, inflammation response scaffold protein. It is constitutively expressed in monocytes and macrophages and is known to be involved in macrophage activation. It is a marker of activated macrophage and widely used as microglial cell marker. Despite a lack of detailed knowledge on the in vivo physiological functions of IBA1, there is growing evidence that shows its aberrant expression contributes to the pathogenesis of many autoimmune diseases, including rheumatoid arthritis. IBA1 is an actin-binding protein that enhances membrane ruffling and RAC activation. It enhances lymphocyte migration and the actin-bundling activity of LCP1. IBA1 also plays a role in RAC signaling and in phagocytosis and involved in vascular inflammation. It also promotes the proliferation of vascular smooth muscle cells and of T-lymphocytes. Properties Storage Instructions All the reagents are stored at 2-8°C. The kit is stable for 6 months from the date of receipt. Synonyms AIF 1, AIF1, G1, IBA1, IRT 1, Protein G1 × Select download options English Czech Danish German Spanish Finnish French Hungarian Italian Lithuanian Dutch Norwegian-Bokmol Polish Portuguese Slovak Swedish Download
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