IHC easy ® KDM3A Ready-To-Use IHC Kit KHC2023 proteintech
$489.00
In stock
SKU
KHC2023
| Product name | IHCeasy KDM3A Ready-To-Use IHC Kit |
| Synonyms | JHDM2A, JHMD2A, JMJD1, JMJD1A, KDM3A, KDM3A,JMJD1A, KIAA0742, lysine (K) demethylase 3A, Lysine specific demethylase 3A, TSGA |
| Reactivity | Human, Mouse, Rat |
| Host / Isotype | United States |
| Sample type | FFPE tissue |
| Assay type | Immunohistochemistry |
| Primary antibody type | Rabbit Polyclonal |
| Secondary antibody type | Polymer-HRP-Goat anti-Rabbit |
| Component | Size Concentration |
| Antigen Retrieval Buffer | 100 mL 50× |
| Washing Buffer | 100 mL ×2 20× |
| Blocking Buffer | 5 mL RTU |
| Primary Antibody | 5 mL RTU |
| Secondary Antibody | 5 mL RTU |
| Chromogen Component A | 0.2 mL RTU |
| Chromogen Component B | 4 mL RTU |
| Signal Enhancer | 5 mL RTU |
| Counter Staining Reagent | 5 mL RTU |
| Mounting Media | 5 mL RTU |
| Datasheet | 1 Copy |
| Manual | 1 Copy |
| Storage Instructions | All the reagents are stored at 2-8°C. The kit is stable for 6 months from the date of receipt. |
KDM3A, also name as JMJD1A, JHDM2A, JMJD1, JMJD1A, KIAA0742 and TSGA, belongs to the JHDM2 histone demethylase family. It is a histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. It is involved in spermatogenesis by regulating expression of target genes such as PRM1 and TMP1 which are required for packaging and condensation of sperm chromatin. It is involved in obesity resistance through regulation of metabolic genes such as PPARA and UCP1. JMJD1A is a useful biomarker for hypoxic tumor cells and a prognostic marker that could be a promising therapeutic target against CRC. Properties Storage Instructions All the reagents are stored at 2-8°C. The kit is stable for 6 months from the date of receipt. Synonyms JHDM2A, JHMD2A, JMJD1, JMJD1A, KDM3A, KDM3A,JMJD1A, KIAA0742, lysine (K) demethylase 3A, Lysine specific demethylase 3A, TSGA × Select download options English Czech Danish German Spanish Finnish French Hungarian Italian Lithuanian Dutch Norwegian-Bokmol Polish Portuguese Slovak Swedish Download
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