Product Information
| Protein full name | Transferrin receptor protein 2 |
| Synonyms | TfR2, Trfr2, HFE3, TFRC2, Transferrin receptor 2 |
| Uniprot ID | Q9JKX3 |
| Immunogen | KLH conjugated Synthetic peptide corresponding to Mouse Transferrin Receptor 2/TFR2 |
| Isotype | IgG |
| Purity | Affinity purification |
| Subcellular location | Cell membrane, Cytoplasm |
Applications
| Applications: IHC/IF | Species: Human, Mouse |
| Dilution: 1: 200-1: 400 | Positive Tissue: liver |
Background
This gene encodes a single-pass type II membrane protein, which is a member of the transferrin receptor-like family. This protein mediates cellular uptake of transferrin-bound iron, and may be involved in iron metabolism, hepatocyte function and erythrocyte differentiation. Mutations in this gene have been associated with hereditary hemochromatosis type III. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Images
IHC analysis of Transferrin Receptor 2/TFR2(GB113731). Sample: Human liver, 4% PFA (G1101) 12-24h. Antigen retrieval: Citrate buffer (pH 6.0) (G1201), 98℃, 20 min. Primary antibody: 1: 200, 4℃ overnight. Secondary antibody: HRP conjugated Goat Anti-Rabbit lgG (H+L) (GB23303), 1: 200, RT, 1h.
IHC analysis of Transferrin Receptor 2/TFR2(GB113731). Sample: Mouse liver, 4% PFA (G1101) 12-24h. Antigen retrieval: Citrate buffer (pH 6.0) (G1201), 98℃, 20 min. Primary antibody: 1: 200, 4℃ overnight. Secondary antibody: HRP conjugated Goat Anti-Rabbit lgG (H+L) (GB23303), 1: 200, RT, 1h.
Storage
| Storage | Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.15% ProClin300, 100 μg/mL BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).