Recombinant Rat IL-1 alpha Protein (His-tag) servicebio GB300001-R-100μg
$50.00
In stock
SKU
GB300001-R-100娓璯
DESCRIPTION
SPECIFICATIONS
STORAGE
BACKGROUND
IL-1 alpha is a member of the interleukin 1 cytokine family. Located in the IL1 cluster, the IL1A gene is a product of IL1B gene duplication, and consequently IL-1α and IL-1β share a receptor, IL-1R1, and its downstream signaling. IL-1α has additional functions, represented by the presence of a nuclear localization signal within its pro-domain. IL-1 alpha is a pleiotropic cytokine involved in various immune responses, inflammatory processes, and hematopoiesis which is proteolytically processed and released in response to cell injury, and thus induces apoptosis. IL-1α is a substrate of noncanonical inflammatory caspases. IL-1 alpha stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity.
Data
Active Recombinant Rat IL-1 alpha Protein was determined by SDS-PAGE with Coomassie Blue.
| Synonym | IL-1 alpha, Il1a, Hematopoietin-1, LEM, LAF, Pro interleukin 1 alpha, IL1F1, Preinterleukin 1 alpha |
| Species | Rat |
| A ccession | P16598 |
| Source | CHO cells |
| Amino acid sequence | Ser115-Ser270 is expressed with a 10×His tag at the C terminus |
| Molecular Weight | 19.2 kDa |
| Purity | >95.0% as determined by SDS-PAGE |
| Endotoxin | <5 EU·mg -1 |
| Formulation | Lyophilized from sterile PBS, pH 7.4.Normally 5%-8% trehalose and mannitol are added as protectants before lyophilization. |
| Reconstitution | Dissolved in sterile water, it is recommended to add 0.1% HSA or BSA for long-term preservation. |
| Stability and Storage | 12 months from date of receipt at -20°C to -70°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for almost 6 months (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage. |
| SDS-PAGE | Bioactivity |
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